Early studies proposed that DNA methylation could have a role in regulating gene
expression during development [Riggs, AD (1975) Cytogenet. Cell Genet. 14, 9–25] …

Alterations in DNA methylation have been implicated in mammalian development. Hence,
the identification of tissue-specific differentially methylated regions (TDMs) is indispensable …

Tissue specific differentially methylated regions (TDMRs) were identified and localized in the
mouse genome using second generation virtual RLGS (vRLGS). Sequenom MassARRAY …

DNA methylation has been implicated in mammalian development. Transcription units
contain CpG islands, but expression of CpG island associated genes in normal tissues was …

Background DNA methylation has been recognized as a key mechanism in cell
differentiation. Various studies have compared tissues to characterize epigenetically …

DNA methylation constitutes an important epigenetic regulation mechanism in many
eukaryotes, although the extent of DNA methylation in the regulation of gene expression in …

Background DNA methylation plays an important role in regulating gene expression during
many biological processes. However, the mechanism of DNA-methylation-dependent gene …

Background Changes in DNA methylation in the mammalian genome during development
are frequent events and play major roles regulating gene expression and other …

Cytosine methylation is required for mammalian development and is often perturbed in
human cancer. To determine how this epigenetic modification is distributed in the genomes …

DNA methylation has been viewed as a stable component of the epigenome, which is
established during development and fixed thereafter. We show here using nearest neighbor …