The role of melatonin in the molecular mechanisms underlying metaflammation and infections in obesity: A narrative review
C Pivonello, M Negri, R Patalano, F Amatrudo… - Obesity …, 2022 - Wiley Online Library
Obesity is a chronic condition whose management is a critical challenge for physicians. The
scientific community has increased its focus on the molecular mechanisms involved in …
scientific community has increased its focus on the molecular mechanisms involved in …
Mechanisms of melatonin in obesity: a review
Q Guan, Z Wang, J Cao, Y Dong, Y Chen - International journal of …, 2021 - mdpi.com
Obesity and its complications have become a prominent global public health problem that
severely threatens human health. Melatonin, originally known as an effective antioxidant, is …
severely threatens human health. Melatonin, originally known as an effective antioxidant, is …
Melatonin in macrophage biology: Current understanding and future perspectives
Y Xia, S Chen, S Zeng, Y Zhao, C Zhu… - Journal of pineal …, 2019 - Wiley Online Library
Melatonin is a ubiquitous hormone found in various organisms and highly affects the
function of immune cells. In this review, we summarize the current understanding of the …
function of immune cells. In this review, we summarize the current understanding of the …
Melatonin supplementation in the management of obesity and obesity-associated disorders: a review of physiological mechanisms and clinical applications
Despite the evolving advances in clinical approaches to obesity and its inherent
comorbidities, the therapeutic challenge persists. Among several pharmacological tools …
comorbidities, the therapeutic challenge persists. Among several pharmacological tools …
Melatonin supplementation attenuates the pro-inflammatory adipokines expression in visceral fat from obese mice induced by a high-fat diet
TSM Farias, RI Paixao, MM Cruz, RDCC de Sa… - Cells, 2019 - mdpi.com
Obesity is defined as a condition of abnormal or excessive fat accumulation in white adipose
tissue that results from the exacerbated consumption of calories associated with low energy …
tissue that results from the exacerbated consumption of calories associated with low energy …
Melatonin supplementation decreases hypertrophic obesity and inflammation induced by high-fat diet in mice
TSM Farias, MM Cruz, RCC Sa, I Severi… - Frontiers in …, 2019 - frontiersin.org
Obesity results from critical periods of positive energy balance characterized by caloric
intake greater than energy expenditure. This disbalance promotes adipose tissue …
intake greater than energy expenditure. This disbalance promotes adipose tissue …
Melatonin mediates mucosal immune cells, microbial metabolism, and rhythm crosstalk: a therapeutic target to reduce intestinal inflammation
Nowadays, melatonin, previously considered only as a pharmaceutical product for rhythm
regulation and sleep aiding, has shown its potential as a co‐adjuvant treatment in intestinal …
regulation and sleep aiding, has shown its potential as a co‐adjuvant treatment in intestinal …
Anti-inflammatory effects of melatonin in obesity and hypertension
Abstract Purpose of Review Here, we review the known relations between hypertension and
obesity to inflammation and postulate the endogenous protective effect of melatonin and its …
obesity to inflammation and postulate the endogenous protective effect of melatonin and its …
Melatonin reduces obesity and restores adipokine patterns and metabolism in obese (ob/ob) mice
G Favero, A Stacchiotti, S Castrezzati, F Bonomini… - Nutrition Research, 2015 - Elsevier
The increasing incidence of obesity, leading to metabolic complications, is now recognized
as a major public health problem. The adipocytes are not merely energy-storing cells, but …
as a major public health problem. The adipocytes are not merely energy-storing cells, but …
[HTML][HTML] The mechanism of oral melatonin ameliorates intestinal and adipose lipid dysmetabolism through reducing Escherichia Coli-derived lipopolysaccharide
B Rong, Q Wu, RJ Reiter, C Sun - Cellular and molecular gastroenterology …, 2021 - Elsevier
Background & Aims Gut microbiota have been reported to be sensitive to circadian rhythms
and host lipometabolism, respectively. Although melatonin-mediated beneficial efforts on …
and host lipometabolism, respectively. Although melatonin-mediated beneficial efforts on …