Methods We conducted an HTA using standard systematic review methodologies. Outcomes
focused on test accuracy and the impact of screening. We did not look for evidence on …

A current doctrine in medicine is that health care should be evidence-based, and an
important tool of evidence-based medicine is health technology assessment (HTA). A typical …

Prenatal/preconceptional and newborn screening programs have been a focus of recent
policy debates that have included attention to ethical, legal, and social issues (ELSIs). In …

Purpose: Cell-free DNA (cfDNA) prenatal screening tests have been rapidly adopted into
clinical practice, due in part to positive insurance coverage. We evaluated the framework …

The province of British Columbia (BC), Canada is developing its first population-wide
prenatal genetic screening program, known as triple-marker screening (TMS). TMS, initiated …

Objectives Health inequality refers to differences in health statuses/outcomes among
people. Health inequity occurs due to unjust and systematic factors. Both relate to reduced …

The inherent normativity of HTA can be conceptualized as a result of normative
commitments, a concept that we further specify to encompass moral, epistemological and …

ObjectivesHealth technology assessment (HTA) can impact health inequities by informing
healthcare priority-setting decisions. This paper presents a novel checklist to guide HTA …

Objectives: Previously in Finland, each municipality selected which methods to use in
screening for fetal abnormalities. This resulted in practice variation and inequity. The …

In January 2017, a group of experts in prenatal genetics attended a workshop at the Society
of Maternal-Fetal Medicine meeting to review the evidence behind the costs and cost …