Genetic variation of the angiotensin‐converting enzyme gene: increased frequency of the insertion allele in Koreans

SH Hong, BY Kang, WH Park, JQ Kim… - Clinical genetics, 1997 - Wiley Online Library
In view of the clinical importance of angiotensin‐converting enzyme (ACE) as a major
marker for cardiovascular diseases, we investigated insertion/deletion (I/D) polymorphism of …

Aorta measurements are heritable and influenced by bicuspid aortic valve

LJ Martin, RB Hinton, X Zhang, LH Cripe… - Frontiers in …, 2011 - frontiersin.org
Objectives: To determine whether the contributions of genetics and bicuspid aortic valve
(BAV) independently influence aortic (Ao) dimensions. Background: Ao dilation is a risk …

A DNA variant at the angiotensin-converting enzyme gene locus associates with coronary artery disease in the Caerphilly Heart Study

RK Mattu, EWA Needham, DJ Galton, E Frangos… - Circulation, 1995 - Am Heart Assoc
Background We analyzed an insertion/deletion (I/D) polymorphism of the angiotensin I–
converting enzyme (ACE) gene in 1226 subjects from the Caerphilly Prospective Heart …

Assessment of genetic risk factors for thoracic aortic aneurysm in hypertensive patients

K Kato, M Oguri, N Kato, T Hibino… - American journal of …, 2008 - academic.oup.com
Background Conventional risk factors for thoracic aortic aneurysm including dissection
(TAA) are thought to include age, arteriosclerosis, and hypertension. In addition, evidence …

[HTML][HTML] Angiotensin-converting enzyme insertion/deletion polymorphism and its association with coronary artery disease in an Iranian population

L Poorgholi, H Saffar, MS Fathollahi… - The Journal of Tehran …, 2013 - ncbi.nlm.nih.gov
Background: The study of the association between genotype and phenotype is of great
importance for the prediction of many diseases and pathophysiological conditions. The …

Angiotensin converting enzyme insertion/deletion polymorphism and the risk of heart failure in hypertensive subjects

AFC Schut, GS Bleumink, BHC Stricker… - European heart …, 2004 - academic.oup.com
Aims Cardiac angiotensin-I converting enzyme (ACE) activity is influenced by the ACE I/D
polymorphism. Evidence suggests that the DD-genotype may be a risk factor for cardiac …

Angiotensin-Converting Enzyme I/D Polymorphism and Arterial Wall Thickness in a General Population: The Vobarno Study

M Castellano, ML Muiesan, D Rizzoni, M Beschi… - Circulation, 1995 - Am Heart Assoc
Background It has been reported that the D allele of an insertion/deletion (I/D) polymorphism
of the angiotensin I–converting enzyme (ACE) gene is associated with conditions of …

Association Between Angiotensin‐Converting Enzyme Gene Polymorphism and Coronary Artery Disease

T Isbir, H Yilmaz, B Agachan, M Aydin, CS Isbir - IUBMB life, 1999 - Wiley Online Library
An insertion/deletion (I/D) polymorphism in the gene for angiotensin‐converting enzyme
(ACE) is associated with myocardial infarction and other cardiac pathology. There is …

Insertion/deletion polymorphism of the angiotensin converting enzyme gene in coronary artery disease in southern Turkey

E Acarturk, G Attila, A Bozkurt, O Akpinar, S Matyar… - BMB …, 2005 - koreascience.kr
Genetic factors are important in the pathogenesis of coronary artery disease (CAD).
Angiotensin converting enzyme (ACE) gene insertion (I)/deletion (D) polymorphism is one of …

Polymorphism of the angiotensin-converting enzyme gene and cardiovascular disease

H Schunkert - Journal of molecular medicine, 1997 - Springer
The angiotensin-converting enzyme (ACE) is an integral part of two enzymatic cascades,
one leading to the generation of angiotensin II and the other to the degradation of …