Methylation of cytosines can mediate epigenetic gene silencing and is the only known DNA
modification in eukaryotes. Recent efforts to map DNA methylation across mammalian …

Methylation of the cytosine base in DNA, DNA methylation, is an essential epigenetic mark
in mammals that contributes to the regulation of transcription. Several advances have been …

One of the most critical epigenetic signatures present in the genome of higher eukaryotes is
the methylation of DNA at the C-5 position of the cytosine ring. Based on the sites of DNA …

DNA methylation is one of the most extensively studied epigenetic marks. It is involved in
transcriptional gene silencing and plays important roles during mammalian development. Its …

Genetic, biochemical and cytological studies on DNA methylation in several eukaryotic
organisms have resulted in leaps of understanding in the past three years. Discoveries of …

DNA methylation was the first epigenetic modification discovered. Until recently,
comprehensive coverage of the composition and distribution of methylated cytosines across …

DNA methylation in mammals is a key epigenetic modification essential to normal genome
regulation and development. DNA methylation patterns are established during early …

Methylation of cytosines is a pervasive feature of eukaryotic genomes and an important
epigenetic layer that is fundamental for cellular differentiation processes and control of …

Cytosine methylation in mammals is an epigenetic modification required for viability of the
developing embryo. It has been suggested that DNA methylation plays important roles in X …

DNA methylation is an epigenetic modification which plays an important role in chromatin
organization and gene expression. DNA methylation can silence genes and repetitive …