DNA methylation constitutes an important epigenetic factor in the control of genetic
information. In this study, we analyzed expression of the DNA methyltransferase gene and …

We have examined the methylation status of the zebrafish genome during early
embryogenesis and we find evidence that methylation fluxes do occur in that organism. The …

DNA methylation is dynamic through the life of an organism. Previous studies have primarily
focused on DNA methylation changes during very early embryogenesis. In this study, global …

methylcytosine is a major epigenetic modification that is sometimes called" the fifth
nucleotide." However, our knowledge of how offspring inherit the DNA methylome from …

Post-fertilization epigenome reprogramming erases epigenetic marks transmitted through
gametes and establishes new marks during mid-blastula stages. The mouse embryo …

DNA methylation reprogramming, the erasure of DNA methylation patterns shortly after
fertilization and their reestablishment during subsequent early development, is essential for …

The levels of genomic DNA methylation in vertebrate species display a wide range of
developmental dynamics. Here, we show that in contrast to mice, the paternal genome of the …

DNA methylation is a prevalent epigenetic modification in vertebrates, and it has been
shown to be involved the regulation of gene expression and embryo development. However …

DNA methylation is crucial for normal development and cellular differentiation in many large-
genome eukaryotes. The small tropical freshwater fish Danio rerio (zebrafish) has recently …

The DNA methylome is re-patterned during discrete phases of vertebrate development. In
zebrafish, there are 2 waves of global DNA demethylation and re-methylation: the first …