Abdominal aortic aneurysms-actual therapeutic strategies

I Droc, D Raithel, B Calinescu - Aneurysm, 2012 - books.google.com
AAA is the thirteenth cause of death in UK accounting for 1.2% of male and 0.6 of female
mortality, and the third cause of sudden death after coronary artery disease and stroke.[1-3] …

Abdominal aortic aneurysm: pathogenesis and implications for management

J Golledge, J Muller, A Daugherty… - … , and vascular biology, 2006 - Am Heart Assoc
Abdominal aortic aneurysm (AAA) affects approximately 5% of elderly men and is
responsible for a significant number of deaths in Western Countries. At present surgery by …

Mechanisms of aortic aneurysm formation: translating preclinical studies into clinical therapies

FM Davis, DL Rateri, A Daugherty - Heart, 2014 - heart.bmj.com
Aneurysms are common in the abdominal and thoracic regions of the aorta. While generally
asymptomatic, progression of aneurysms is associated with the devastating consequences …

Antithrombotic therapy in abdominal aortic aneurysm: beneficial or detrimental?

SJ Cameron, HM Russell… - Blood, The Journal of the …, 2018 - ashpublications.org
Abdominal aortic aneurysm (AAA) is a degenerative vascular pathology resulting in
significant morbidity and mortality in older adults due to rupture and sudden death. Despite …

Angiotensin II and abdominal aortic aneurysms: an update

J Liu, A Daugherty, H Lu - Current pharmaceutical design, 2015 - ingentaconnect.com
Abdominal aortic aneurysm (AAA) is a devastating disease associated with high prevalence
of death due to aortic rupture. Currently the therapy is restricted to surgical procedures to …

[HTML][HTML] Potential of disease-modifying anti-rheumatic drugs to limit abdominal aortic aneurysm growth

S Thanigaimani, M Ibrahim, J Golledge - Biomedicines, 2022 - mdpi.com
Inflammation is strongly implicated in the pathogenesis of abdominal aortic aneurysms
(AAA). This review examined the potential role of biologic disease-modifying anti-rheumatic …

Top 10 candidate aortic disease trials

RL Dalman, A Wanhainen, K Mani… - Journal of Internal …, 2020 - Wiley Online Library
Aortic pathologies such as aneurysm, dissection and trauma are relatively common and
potentially fatal diseases. Over the past two decades, we have experienced unprecedented …

Abdominal aortic aneurysm: evolving controversies and uncertainties

D Carino, TP Sarac, BA Ziganshin… - … Journal of angiology, 2018 - thieme-connect.com
Abdominal aortic aneurysm (AAA) is defined as a permanent dilatation of the abdominal
aorta that exceeds 3 cm. Most AAAs arise in the portion of abdominal aorta distal to the renal …

[HTML][HTML] Pharmacological interventions to attenuate the expansion of abdominal aortic aneurysm (AAA)–a systematic review

D Bergqvist - European Journal of Vascular and Endovascular …, 2011 - Elsevier
INTRODUCTION: Is it possible by pharmacological methods to attenuate the expansion rate
of abdominal aortic aneurysms? METHOD: An Internet-based systematic literature search …

The impact of recent European trials on abdominal aortic aneurysm repair: is a paradigm shift warranted?

RL Bush, L Mureebe, WT Bohannon… - Journal of Surgical …, 2008 - Elsevier
Recent reports, following upon the reported outcomes of European randomized prospective
trials of endovascular abdominal aortic aneurysm repair (EVAR), have brought into question …