Objective We determined the potential programming effects of maternal obesity and high-fat
(HF) diet during pregnancy and/or lactation on offspring metabolic syndrome. Study Design …

Childhood obesity is associated with increased risk of behavioral/psychological disorders
including depression, anxiety, poor learning, and attention deficient disorder. As the majority …

Maternal obesity has long‐term consequences for the development of hypothalamic
neurones involved in energy homeostasis and the metabolic profile in offspring. In the …

Objective: Key appetite regulators and their receptors are already present in the fetal
hypothalamus, and may respond to hormones such as leptin. Intrauterine food restriction or …

Key points• Perinatal maternal high‐fat diet changes milk composition, resulting in obesity
and hyperglycaemia in male offspring at weaning.• Offspring obesity is associated with …

There is a growing body of evidence linking maternal overnutrition to obesity and
psychopathology that can be conserved across multiple generations. Recently, we …

Maternal obesity can profoundly affect offspring phenotype and predisposition to obesity and
metabolic disease. Carefully controlled studies in precocial and altricial mammalian species …

Rationale Early environment can shape the development and function of the
mesocorticolimbic dopamine (DA) system and represents a possible risk factor for adult …

Obesity involving women of reproductive years is increasing dramatically in both developing
and developed nations. Maternal obesity and accompanying high energy obesogenic …

The environment that a developing offspring experiences during the perinatal period is
markedly influenced by maternal health and diet composition. Evidence from both …