Dietary and supplemental maternal methyl-group donor intake and cord blood DNA methylation
Maternal nutrition is critically involved in the development and health of the fetus. We
evaluated maternal methyl-group donor intake through diet (methionine, betaine, choline …
evaluated maternal methyl-group donor intake through diet (methionine, betaine, choline …
[HTML][HTML] Alterations in the placental methylome with maternal obesity and evidence for metabolic regulation
The inflammatory and metabolic derangements of obesity in pregnant women generate an
adverse intrauterine environment, increase pregnancy complications and adverse fetal …
adverse intrauterine environment, increase pregnancy complications and adverse fetal …
[HTML][HTML] Epigenetic modulation of DNA methylation by nutrition and its mechanisms in animals
N Zhang - Animal nutrition, 2015 - Elsevier
It is well known that phenotype of animals may be modified by the nutritional modulations
through epigenetic mechanisms. As a key and central component of epigenetic network …
through epigenetic mechanisms. As a key and central component of epigenetic network …
[HTML][HTML] Breastfeeding effects on DNA methylation in the offspring: A systematic literature review
Background Breastfeeding benefits both infants and mothers. Recent research shows long-
term health and human capital benefits among individuals who were breastfed. Epigenetic …
term health and human capital benefits among individuals who were breastfed. Epigenetic …
Male germline transmits fetal alcohol adverse effect on hypothalamic proopiomelanocortin gene across generations
D Govorko, RA Bekdash, C Zhang, DK Sarkar - Biological psychiatry, 2012 - Elsevier
BACKGROUND: Neurons containing proopiomelanocortin (POMC)-derived peptides, known
to control stress axis, metabolic, and immune functions, have a lower function in patients …
to control stress axis, metabolic, and immune functions, have a lower function in patients …
[HTML][HTML] Sperm histone H3 lysine 4 tri-methylation serves as a metabolic sensor of paternal obesity and is associated with the inheritance of metabolic dysfunction
Objective Parental environmental exposures can strongly influence descendant risks for
adult disease. How paternal obesity changes the sperm chromatin leading to the acquisition …
adult disease. How paternal obesity changes the sperm chromatin leading to the acquisition …
[HTML][HTML] Epigenetics: linking early postnatal nutrition to obesity programming?
L Marousez, J Lesage, D Eberlé - Nutrients, 2019 - mdpi.com
Despite constant research and public policy efforts, the obesity epidemic continues to be a
major public health threat, and new approaches are urgently needed. It has been shown that …
major public health threat, and new approaches are urgently needed. It has been shown that …
Intergenerational transmission of DNA methylation signatures associated with early life stress
L Stenz, DS Schechter, SR Serpa… - Current …, 2018 - ingentaconnect.com
Early life stress in humans (ie maltreatment, violence exposure, loss of a loved one) and in
rodents (ie disrupted attachment or nesting, electric shock, restraint, predator odor) occurs …
rodents (ie disrupted attachment or nesting, electric shock, restraint, predator odor) occurs …