During early mammalian embryogenesis, there is a wave of DNA demethylation
postfertilization and de novo methylation around implantation. The paternal genome …

The aim of this study was to demonstrate how differential methylation imprints are
established during porcine preimplantation embryo development. For the methylation …

Preimplantation embryos experience profound resetting of epigenetic information inherited
from the gametes. Genome-wide analysis at single-base resolution has shown similarities …

DNA methylation is an important epigenetic modification that undergoes dynamic changes
in mammalian embryogenesis, during which both parental genomes are reprogrammed …

The recent identification of an intragenic differentially methylated region (DMR) within the
last exon of the bovine Insulin-like growth factor 2 (IGF2) gene provides a diagnostic tool for …

Genomic imprinting plays a very important role during development and its abnormality may
heavily undermine the developmental potential of bovine embryos. Because of limited …

Background In mammals, maternal differentially methylated regions (DMRs) acquire DNA
methylation during the postnatal growth stage of oogenesis, with paternal DMRs acquiring …

This study was designed to identify the putative differentially methylated regions (DMRs) of
the porcine imprinted genes insulin‐like growth factor 2 and H19 (IGF2‐H19), and to assess …

DNA methylation undergoes drastic fluctuation during early mammalian embryogenesis.
The dynamics of global DNA methylation in bovine embryos, however, have mostly been …

Critical epigenetic regulation of primate embryogenesis entails DNA methylome changes.
Here we report genome-wide composition, patterning, and stage-specific dynamics of DNA …