DNA methylation dynamics underlie metamorphic gene regulation programs in Xenopus tadpole brain

Y Kyono, S Raj, CJ Sifuentes, N Buisine, L Sachs… - Developmental …, 2020 - Elsevier
Methylation of cytosine residues in DNA influences chromatin structure and gene
transcription, and its regulation is crucial for brain development. There is mounting evidence …

Embryonic DNA methylation: insights from the genomics era

O Bogdanović… - Briefings in functional …, 2014 - academic.oup.com
DNA methylation is an epigenetic mark associated with transcriptional repression and
essential for proper vertebrate development. Because of its association with human …

DNA methylation profile dynamics of tissue-dependent and differentially methylated regions during mouse brain development

K Hirabayashi, K Shiota, S Yagi - BMC genomics, 2013 - Springer
Background Tissues and their component cells have unique DNA methylation profiles
comprising DNA methylation patterns of tissue-dependent and differentially methylated …

Evolutionary conservation of embryonic DNA methylome remodelling in distantly related teleost species

SE Ross, J Vázquez-Marín, KRB Gert… - Nucleic Acids …, 2023 - academic.oup.com
Methylation of cytosines in the CG context (mCG) is the most abundant DNA modification in
vertebrates that plays crucial roles in cellular differentiation and identity. After fertilization …

Comparative analysis of genome-scale, base-resolution DNA methylation profiles across 580 animal species

J Klughammer, D Romanovskaia, A Nemc… - Nature …, 2023 - nature.com
Methylation of cytosines is a prototypic epigenetic modification of the DNA. It has been
implicated in various regulatory mechanisms across the animal kingdom and particularly in …

Active DNA demethylation at enhancers during the vertebrate phylotypic period

O Bogdanović, AH Smits, E de la Calle Mustienes… - Nature …, 2016 - nature.com
The vertebrate body plan and organs are shaped during a conserved embryonic phase
called the phylotypic stage. However, the mechanisms that guide the epigenome through …

Developmental enhancers revealed by extensive DNA methylome maps of zebrafish early embryos

HJ Lee, RF Lowdon, B Maricque, B Zhang… - Nature …, 2015 - nature.com
DNA methylation undergoes dynamic changes during development and cell differentiation.
Recent genome-wide studies discovered that tissue-specific differentially methylated …

Epigenetic modification of the hypothalamic–pituitary–adrenal (HPA) axis during development in the house sparrow (Passer domesticus)

SJS Wilks, DF Westneat, BJ Heidinger… - General and …, 2023 - Elsevier
Epigenetic modifications such as DNA methylation are important mechanisms for mediating
developmental plasticity, where ontogenetic processes and their phenotypic outcomes are …

Reprogramming of DNA methylation at NEUROD2-bound sequences during cortical neuron differentiation

MA Hahn, SG Jin, AX Li, J Liu, Z Huang, X Wu… - Science …, 2019 - science.org
The characteristics of DNA methylation changes that occur during neurogenesis in vivo
remain unknown. We used whole-genome bisulfite sequencing to quantitate DNA cytosine …

DNA methylation regulates transcription factor-specific neurodevelopmental but not sexually dimorphic gene expression dynamics in zebra finch telencephalon

J Diddens, L Coussement, C Frankl-Vilches… - Frontiers in Cell and …, 2021 - frontiersin.org
Song learning in zebra finches (Taeniopygia guttata) is a prototypical example of a complex
learned behavior, yet knowledge of the underlying molecular processes is limited …