Abstract Rationale and Objectives Addiction is defined as a chronically relapsing disorder
characterized by compulsive drug seeking that is hypothesized to derive from multiple …

The loss of control over drug use that characterizes addiction develops progressively over
time as a result of drug-induced changes in the brain. Chronic substance use leads to the …

The dopamine pathway is helping researchers find their way through the addiction maze ur
flourishing knowledge of the brain is in large part the product of research on addiction …

The main thane of this lecture is the study of drug‐dependence through its interactions with
other pharmacologically or physiologically active substances, particularly those known to …

This paper reviews the principal theoretical models of drug craving and provides some
directions for future research. The main models are classified broadly into three …

This concluding chapter offers an overview of some issues raised in the book. Future
developments in theory and research include seeing addiction as dynamic inconsistency …

Substance abuse or addictive disorder is a global problem. A greater understanding of the
associated changes in brain pathophysiology supports the notion that pharmacological …

There are many sources of reinforcement in the spectrum of cocaine dependence that
contribute to the compulsive cocaine self-administration or loss of control of cocaine intake …

Large portions of the general population will not only experience a form of mental illness
during the course of their lifetime, but will also experience some form of addiction. Drug …

Chronic vulnerability to relapse is a formidable challenge for the treatment of drug addiction.
The neurobiological basis of relapse and its prevention has, therefore, attracted major …