An evaluation of analysis pipelines for DNA methylation profiling using the Illumina HumanMethylation450 BeadChip platform

F Marabita, M Almgren, ME Lindholm, S Ruhrmann… - Epigenetics, 2013 - Taylor & Francis
The proper identification of differentially methylated CpGs is central in most epigenetic
studies. The Illumina HumanMethylation450 BeadChip is widely used to quantify DNA …

Complete Pipeline for Infinium® Human Methylation 450K BeadChip Data Processing Using Subset Quantile Normalization for Accurate DNA Methylation Estimation

N Touleimat, J Tost - Epigenomics, 2012 - Taylor & Francis
Background: Huge progress has been made in the development of array-or sequencing-
based technologies for DNA methylation analysis. The Illumina Infinium® Human …

missMethyl: an R package for analyzing data from Illumina's HumanMethylation450 platform

B Phipson, J Maksimovic, A Oshlack - Bioinformatics, 2015 - academic.oup.com
DNA methylation is one of the most commonly studied epigenetic modifications due to its
role in both disease and development. The Illumina HumanMethylation450 BeadChip is a …

A data-driven approach to preprocessing Illumina 450K methylation array data

R Pidsley, CC Y Wong, M Volta, K Lunnon, J Mill… - BMC genomics, 2013 - Springer
Background As the most stable and experimentally accessible epigenetic mark, DNA
methylation is of great interest to the research community. The landscape of DNA …

The ENmix DNA methylation analysis pipeline for Illumina BeadChip and comparisons with seven other preprocessing pipelines

Z Xu, L Niu, JA Taylor - Clinical epigenetics, 2021 - Springer
Background Illumina DNA methylation arrays are high-throughput platforms for cost-effective
genome-wide profiling of individual CpGs. Experimental and technical factors introduce …

Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling

R Pidsley, E Zotenko, TJ Peters, MG Lawrence… - Genome biology, 2016 - Springer
Background In recent years the Illumina HumanMethylation450 (HM450) BeadChip has
provided a user-friendly platform to profile DNA methylation in human samples. However …

A framework for analyzing DNA methylation data from Illumina Infinium HumanMethylation450 BeadChip

Z Wang, XL Wu, Y Wang - BMC bioinformatics, 2018 - Springer
Background DNA methylation has been identified to be widely associated to complex
diseases. Among biological platforms to profile DNA methylation in human, the Illumina …

Validation of a DNA methylation microarray for 850,000 CpG sites of the human genome enriched in enhancer sequences

S Moran, C Arribas, M Esteller - Epigenomics, 2016 - Taylor & Francis
Aim: DNA methylation is the best known epigenetic mark. Cancer and other pathologies
show an altered DNA methylome. However, delivering complete DNA methylation maps is …

SWAN: Subset-quantile within array normalization for illumina infinium HumanMethylation450 BeadChips

J Maksimovic, L Gordon, A Oshlack - Genome biology, 2012 - Springer
DNA methylation is the most widely studied epigenetic mark and is known to be essential to
normal development and frequently disrupted in disease. The Illumina …

ChAMP: updated methylation analysis pipeline for Illumina BeadChips

Y Tian, TJ Morris, AP Webster, Z Yang, S Beck… - …, 2017 - academic.oup.com
Abstract Summary The Illumina Infinium HumanMethylationEPIC BeadChip is the new
platform for high-throughput DNA methylation analysis, effectively doubling the coverage …