Vertebrate development begins with precise molecular, cellular, and morphogenetic controls
to establish the basic body plan of the embryo. In zebrafish, these tightly regulated …

In zebrafish, the program for dorsal specification begins soon after fertilization. Dorsal
determinants are localized initially to the vegetal pole, then transported to the blastoderm …

The basic vertebrate body plan of the zebrafish embryo is established in the first 10 hours of
development. This period is characterized by the formation of the anterior-posterior and …

We identified 6 genes that are essential for specifying ventral regions of the early zebrafish
embryo. Mutations in these genes cause an expansion of structures normally derived from …

In vertebrates, the animal–vegetal axis is determined during oogenesis and at ovulation, the
egg is radially symmetric. In anamniotes, following fertilization, a microtubule-dependent …

A fundamental question in developmental biology is how the early embryo establishes the
spatial coordinate system that is later important for the organization of the embryonic body …

Publisher Summary Cellular and molecular mechanisms involved in the establishment of the
zebrafish embryonic body plan appear strikingly similar to those operating in amphibians or …

Lineage tracing studies carried out in amphibian, fish, mouse and chicken embryos have
shown that the fate of cells in the older animal can be traced to the positions of their …

A large collection of mutations affecting zebrafish embryogenesis was described in 1996.
The cloning of the affected genes has now provided novel insights into the role and …

Recent advances in our understanding of axis formation and patterning in zebrafish relate
the developmental mode of this aspiring genetic model organism to higher vertebrates. The …