Oriented cell division is an integral part of pattern development in processes ranging from
asymmetric segregation of cell-fate determinants to the shaping of tissues,. Despite …

Bone morphogenetic proteins (BMPs) are key mediators of dorsoventral patterning in
vertebrates and are required for the induction of ventral fates in fish and frogs. A widely …

Several components of noncanonical Wnt signaling pathways are involved in the control of
convergence and extension (CE) movements during zebrafish and Xenopus gastrulation …

ABSTRACT A bone morphogenetic protein (BMP) signaling pathway acts in the
establishment of the dorsoventral axis of the vertebrate embryo. Here we demonstrate the …

Gastrulation is the period of development when the three germ layers, mesoderm, endoderm
and ectoderm, are not only formed, but also shaped into a rudimentary body plan. An …

Recent revisions in the Xenopus laevis fate map led to the designation of the rostral/caudal
axis and reassignment of the dorsal/ventral axis (Lane and Smith [1999] Development 126 …

The establishment of anteroposterior (AP) polarity in the early mouse epiblast is crucial for
the initiation of gastrulation and the subsequent formation of the embryonic (head to tail) …

Dorsoventral (DV) axis formation of the vertebrate embryo is controlled by the maternal
genome and is subsequently refined zygotically. In the zygote, repression of ventralizing …

Combinatorial signaling is an important mechanism that allows the embryo to utilize
overlapping signaling pathways to specify different territories. In zebrafish, the Wnt and Bmp …

The secreted TGF-β superfamily signals Nodal and BMP coordinate the patterning of
vertebrate embryos. Nodal specifies endoderm and mesoderm during germ layer formation …