The application of next generation sequencing in DNA methylation analysis
Y Zhang, A Jeltsch - Genes, 2010 - mdpi.com
DNA methylation is a major form of epigenetic modification and plays essential roles in
physiology and disease processes. In the human genome, about 80% of cytosines in the 56 …
physiology and disease processes. In the human genome, about 80% of cytosines in the 56 …
DNA methylation detection: bisulfite genomic sequencing analysis
Y Li, TO Tollefsbol - Epigenetics protocols, 2011 - Springer
DNA methylation, which most commonly occurs at the C5 position of cytosines within CpG
dinucleotides, plays a pivotal role in many biological procedures such as gene expression …
dinucleotides, plays a pivotal role in many biological procedures such as gene expression …
Determining DNA methylation profiles using sequencing
Cytosine methylation is an epigenetic mark that has a significant impact on the regulation of
transcription and replication of DNA. DNA methylation patterns are highly conserved across …
transcription and replication of DNA. DNA methylation patterns are highly conserved across …
Targeted bisulfite sequencing for biomarker discovery
Cytosine methylation is one of the best studied epigenetic modifications. In mammals, DNA
methylation patterns vary among cells and is mainly found in the CpG context. DNA …
methylation patterns vary among cells and is mainly found in the CpG context. DNA …
Comprehensive evaluation of commercial bisulfite-based DNA methylation kits and development of an alternative protocol with improved conversion performance
S Tierling, B Schmitt, J Walter - Genetics & epigenetics, 2018 - journals.sagepub.com
DNA methylation is the most studied epigenetic modification with a wide range of regulatory
functions in mammalian genomes. It almost exclusively resides on CpG dinucleotides and …
functions in mammalian genomes. It almost exclusively resides on CpG dinucleotides and …
Targeted DNA methylation analysis by next-generation sequencing
DR Masser, DR Stanford, WM Freeman - JoVE (Journal of Visualized …, 2015 - jove.com
The role of epigenetic processes in the control of gene expression has been known for a
number of years. DNA methylation at cytosine residues is of particular interest for epigenetic …
number of years. DNA methylation at cytosine residues is of particular interest for epigenetic …
Genome‐wide DNA methylation profiling
M Bibikova, JB Fan - Wiley Interdisciplinary Reviews: Systems …, 2010 - Wiley Online Library
DNA methylation plays a critical role in the regulation of gene expression. The ability to
access the methylation status for a large number of genes or the entire genome should …
access the methylation status for a large number of genes or the entire genome should …
A summary of the biological processes, disease-associated changes, and clinical applications of DNA methylation
GB Andersen, J Tost - DNA Methylation Protocols, 2018 - Springer
DNA methylation at cytosines followed by guanines, CpGs, forms one of the multiple layers
of epigenetic mechanisms controlling and modulating gene expression through chromatin …
of epigenetic mechanisms controlling and modulating gene expression through chromatin …
CpGtools: a python package for DNA methylation analysis
Motivation DNA methylation can be measured at the single CpG level using sodium bisulfite
conversion of genomic DNA followed by sequencing or array hybridization. Many analytic …
conversion of genomic DNA followed by sequencing or array hybridization. Many analytic …
Current and emerging technologies for the analysis of the genome-wide and locus-specific DNA methylation patterns
J Tost - DNA Methyltransferases-Role and Function, 2016 - Springer
DNA methylation is the most studied epigenetic modification, and altered DNA methylation
patterns have been identified in cancer and more recently also in many other complex …
patterns have been identified in cancer and more recently also in many other complex …