▪ Abstract Reactive oxygen intermediates are produced in all aerobic organisms during
respiration and exist in the cell in a balance with biochemical antioxidants. Excess reactive …

Reactive oxygen species are produced by all aerobic cells and are widely believed to play a
pivotal role in aging as well as a number of degenerative diseases. The consequences of …

The utilization of molecular oxygen as the terminal electron acceptor for energy production
has in many ways shaped the evolution of complex life, physiology, and certain disease …

Oxidative stress resulting from toxic effects of reactive oxygen species (ROS) plays an
important role in the pathogenesis of a variety of diseases and important biological …

Reactive oxygen species (ROS) are implicated in the pathogenesis of a wide variety of
human diseases. Recent evidence suggests that at moderately high concentrations, certain …

Reactive oxygen species (ROS) including superoxide anion and hydrogen peroxide (H 2 O
2) are thought to be byproducts of aerobic respiration with damaging effects on DNA …

In aerobic organisms, oxygen is essential for efficient energy production but paradoxically,
produces chronic toxic stress in cells. Diverse protective systems must exist to enable …

We review gases that can affect oxidative stress and that themselves may be radicals. We
discuss O2 toxicity, invoking superoxide, hydrogen peroxide, and the hydroxyl radical. We …

Reactive oxygen species contribute to the pathogenesis of a number of disparate disorders
including tissue inflammation, heart failure, hypertension, and atherosclerosis. In response …

Molecular oxygen (O2) is the premier biological electron acceptor that serves vital roles in
fundamental cellular functions. However, with the beneficial properties of O2 comes the …