Melatonin, aging, and COVID-19: Could melatonin be beneficial for COVID-19 treatment in the elderly?

G Öztürk, KG Akbulut, Ş Güney - Turkish journal of medical …, 2020 - journals.tubitak.gov.tr
The aim of this review is to summarize current studies on the relationship between melatonin
and aging. Nowadays, age-related diseases come into prominence, and identifying age …

Melatonin: roles in influenza, Covid‐19, and other viral infections

G Anderson, RJ Reiter - Reviews in medical virology, 2020 - Wiley Online Library
There is a growing appreciation that the regulation of the melatonergic pathways, both
pineal and systemic, may be an important aspect in how viruses drive the cellular changes …

Melatonin as adjuvant treatment for coronavirus disease 2019 pneumonia patients requiring hospitalization (MAC-19 PRO): a case series

RR Castillo, GRA Quizon, MJM Juco… - Melatonin …, 2020 - melatonin-research.net
Abstract Treatment for coronavirus disease 2019 (COVID19) pneumonia remains empirical
and the search for therapies that can improve outcomes continues. Melatonin has been …

From implantation to birth: insight into molecular melatonin functions

G Carlomagno, M Minini, M Tilotta, V Unfer - International journal of …, 2018 - mdpi.com
Melatonin is a lipophilic hormone synthesized and secreted mainly in the pineal gland,
acting as a neuroendocrine transducer of photoperiodic information during the night. In …

Melatonin interferes with COVID-19 at several distinct ROS-related steps

OG Camp, D Bai, DC Gonullu, N Nayak… - Journal of Inorganic …, 2021 - Elsevier
Recent studies have shown a correlation between COVID-19, caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, and the distinct, exaggerated …

Melatonin: an established antioxidant worthy of use in clinical trials

A Korkmaz, RJ Reiter, T Topal, LC Manchester… - Molecular …, 2009 - Springer
Oxidative stress plays a key role in the pathogenesis of aging and many metabolic diseases;
therefore, an effective antioxidant therapy would be of great importance in these …

Melatonin and its atheroprotective effects: a review

G Favero, LF Rodella, RJ Reiter, R Rezzani - Molecular and cellular …, 2014 - Elsevier
Atherosclerosis is a chronic vascular disease in which oxidative stress and inflammation are
commonly implicated as major causative factors. Identification of novel strategies that …

Use of melatonin in oxidative stress related neonatal diseases

G D'Angelo, R Chimenz, RJ Reiter, E Gitto - Antioxidants, 2020 - mdpi.com
Reactive oxygen species have a crucial role in the pathogenesis of perinatal diseases.
Exposure to inflammation, infections, or high oxygen concentrations is frequent in preterm …

Potential utility of melatonin in preeclampsia, intrauterine fetal growth retardation, and perinatal asphyxia

L Marseglia, G D'Angelo, S Manti… - Reproductive …, 2016 - journals.sagepub.com
Aim: Reactive oxygen species play an important role in the pathogenesis of several
diseases during gestation and the perinatal period. During pregnancy, increased oxygen …

Potential utility of melatonin as an antioxidant during pregnancy and in the perinatal period

S Aversa, S Pellegrino, I Barberi… - The Journal of …, 2012 - Taylor & Francis
Reactive oxygen species (ROS) play a critical role in the pathogenesis of various diseases
during pregnancy and the perinatal period. Newborns are more prone to oxidative stress …