Neonatal seizures: treatment and treatment variability in 31 United States pediatric hospitals

HK Blume, MM Garrison… - Journal of child …, 2009 - journals.sagepub.com
Neonatal seizures are one of the most common neurological disorders in infants. However,
the optimal treatment strategy for neonatal seizures remains controversial and there is little …

Recent advances in the diagnosis and treatment of neonatal seizures

D Samanta - Neuropediatrics, 2021 - thieme-connect.com
Seizures are the most common neurological emergency in the neonates, and this age group
has the highest incidence of seizures compared with any other period of life. The author …

The use of phenobarbital and other anti-seizure drugs in newborns

M El-Dib, JS Soul - Seminars in Fetal and Neonatal Medicine, 2017 - Elsevier
Neonatal seizures constitute the most frequent presenting neurologic sign encountered in
the neonatal intensive care unit. Despite limited efficacy and safety data, phenobarbital …

Neonatal seizures: dilemmas in workup and management

H Bassan, Y Bental, E Shany, I Berger, P Froom… - Pediatric …, 2008 - Elsevier
There is a pressing need for consistent, evidence-based guidelines in the management of
neonatal seizures by pediatric neurologists and neonatologists. Israeli pediatric neurologists …

Off-label use of antiepileptic drugs for the treatment of neonatal seizures

FS Silverstein, DM Ferriero - Pediatric neurology, 2008 - Elsevier
Medically refractory neonatal seizures represent a major therapeutic challenge in neonatal
intensive care units. Conventional antiepileptic drugs demonstrate limited efficacy. Previous …

Response to antiseizure medications in neonates with acute symptomatic seizures

HC Glass, JS Soul, CJ Chu, SL Massey… - …, 2019 - Wiley Online Library
In a prospective cohort of 534 neonates with acute symptomatic seizures, 66% had
incomplete response to the initial loading dose of antiseizure medication (ASM). Treatment …

Neonatal seizures

ML Zupanc - Pediatric Clinics, 2004 - pediatric.theclinics.com
Neonatal seizures are poorly classified, under-recognized, and often difficult to treat. The
presence of neonatal seizures often signals an underlying ominous neurological condition …

Improving the treatment of neonatal seizures: National Institute of Neurological Disorders and Stroke workshop report

FS Silverstein, FE Jensen, T Inder… - The Journal of …, 2008 - jpeds.com
In childhood, the risk of seizures is highest in the neonatal period (1.8 to 3.5/1000 live births
in the United States). Neonatal seizures (NS) are associated with high mortality and …

Effect of treatment of clinical seizures vs electrographic seizures in full-term and near-term neonates: a randomized clinical trial

RW Hunt, HG Liley, D Wagh, R Schembri… - JAMA network …, 2021 - jamanetwork.com
Importance Seizures in the neonatal period are associated with increased mortality and
morbidity. Bedside amplitude-integrated electroencephalography (aEEG) has facilitated the …

Clinical management of seizures in newborns: diagnosis and treatment

LGM van Rooij, MPH van den Broek, CMA Rademaker… - Pediatric Drugs, 2013 - Springer
Neonatal seizures can be classified as tonic, clonic, myoclonic, and subtle. A clinical
diagnosis is not easy as seizures are usually subtle in neonates. In the majority of newborn …