The newborn drug development initiative workshop: summary proceedings from the neurology group on neonatal seizures

RR Clancy - Clinical therapeutics, 2006 - Elsevier
BACKGROUND:: The neonatal period eclipses all other epochs of the human life span for
the highest incidence of seizures. Neonatal seizures are most commonly incited by serious …

[HTML][HTML] Levetiracetam versus phenobarbital for neonatal seizures: a retrospective cohort study

L Bättig, C Dünner, D Cserpan, A Rüegger… - Pediatric …, 2023 - Elsevier
Background Although phenobarbital (PB) is commonly used as a first-line antiseizure
medication (ASM) for neonatal seizures, in 2015 we chose to replace it with levetiracetam …

Neonatal seizures—perspective in low-and middle-income countries

H Vegda, V Krishnan, G Variane, V Bagayi… - Indian Journal of …, 2022 - Springer
Neonatal seizures are the commonest neurological emergency and are associated with
poor neurodevelopmental outcome. While they are generally difficult to diagnose and treat …

Medical treatment in infants and young children with epilepsy: off‐label use of antiseizure medications. Survey Report of ILAE Task Force Medical Therapies in …

J Sourbron, S Auvin, A Arzimanoglou, JH Cross… - Epilepsia …, 2023 - Wiley Online Library
Abstract Objective Antiseizure medications (ASMs) remain the mainstay of epilepsy
treatment. These ASMs have mainly been tested in trials in adults with epilepsy, which …

Drug treatment of neonatal seizures by neonatologists and paediatric neurologists

KB Carmo, P Barr - Journal of paediatrics and child health, 2005 - Wiley Online Library
Objective: To survey anti‐epileptic drug (AED) treatment of early‐onset neonatal seizures by
neonatologists and paediatric neurologists. Methods: A self‐administered questionnaire was …

A comparison of levetiracetam and phenobarbital for the treatment of neonatal seizures associated with hypoxic–ischemic encephalopathy

LM Rao, SA Hussain, T Zaki, A Cho, T Chanlaw… - Epilepsy & Behavior, 2018 - Elsevier
Purpose Seizures are common in term infants with hypoxic–ischemic encephalopathy (HIE)
undergoing therapeutic hypothermia. Although phenobarbital (PHB) is generally considered …

Neonatal seizures—are we there yet?

G Ramantani, B Schmitt, B Plecko, RM Pressler… - …, 2019 - thieme-connect.com
Neonatal seizures are the most prevalent and distinctive sign of neurologic dysfunction in
early life and pose an immense challenge for clinicians. Improvements in neonatal care …

Neonatal seizures: impact on neurodevelopmental outcomes

SK Kang, SD Kadam - frontiers in Pediatrics, 2015 - frontiersin.org
Neonatal period is the most vulnerable time for the occurrence of seizures, and neonatal
seizures often pose a clinical challenge both for their acute management and frequency of …

Neonatal seizures: a review of outcomes and outcome predictors

F Pisani, C Spagnoli - Neuropediatrics, 2016 - thieme-connect.com
The majority of neonatal seizures are of acute symptomatic origin, and their occurrence is
associated with higher mortality and morbidity compared with the general population, even if …

Neonatal seizures: controversies and challenges in translating new therapies from the lab to the isolette

KE Chapman, YH Raol… - European Journal of …, 2012 - Wiley Online Library
Neonatal seizures have unique properties that have proved challenging for both clinicians
and basic science researchers. Clinical therapies aimed at neonatal seizures have proven …