Effect of blood pressure lowering drugs and antibiotics on abdominal aortic aneurysm growth: a systematic review and meta-analysis

J Golledge, TP Singh - Heart, 2021 - heart.bmj.com
Objective There is currently no medical treatment proven to limit abdominal aortic aneurysm
(AAA) progression. The aim of this systematic review and meta-analysis was to pool data …

Pharmacotherapy in clinical trials for abdominal aortic aneurysms: A systematic review and meta-analysis

Z Su, J Guo, Y Gu - Clinical and Applied Thrombosis …, 2022 - journals.sagepub.com
Objective There is no medical treatment proven to limit abdominal aortic aneurysm (AAA)
progression. This systematic review aimed to summarise available trial evidence on the …

Pathogenesis and management of abdominal aortic aneurysm

J Golledge, S Thanigaimani, JT Powell… - European Heart …, 2023 - academic.oup.com
Abdominal aortic aneurysm (AAA) causes∼ 170 000 deaths annually worldwide. Most
guidelines recommend asymptomatic small AAAs (30 to< 50 mm in women; 30 to< 55 mm in …

[HTML][HTML] Blood pressure, hypertension and the risk of abdominal aortic aneurysms: a systematic review and meta-analysis of cohort studies

E Kobeissi, M Hibino, H Pan, D Aune - European journal of epidemiology, 2019 - Springer
Abdominal aortic aneurysms (AAA) are fatal in 80% of the cases when ruptured.
Hypertension has been considered a potential risk factor for AAA; but the findings from …

Current theories and clinical trial evidence for limiting human abdominal aortic aneurysm growth

J Yu, S Liu, J Huang, W Wang - Current drug targets, 2018 - ingentaconnect.com
Background: Abdominal aortic aneurysm (AAA) refers to localized dilation of abdominal
aorta. AAA is largely asymptomatic, but aneurysmal rupture results in a high mortality rate …

Lack of an effective drug therapy for abdominal aortic aneurysm

J Golledge, JV Moxon, TP Singh… - Journal of internal …, 2020 - Wiley Online Library
Abdominal aortic aneurysm (AAA) rupture is a common cause of death in adults. Current
AAA treatment is by open surgical or endovascular aneurysm repair. Rodent model and …

[HTML][HTML] Challenges and opportunities in limiting abdominal aortic aneurysm growth

J Golledge, PE Norman, MP Murphy… - Journal of vascular …, 2017 - Elsevier
Objective This review describes ongoing efforts to develop a medical therapy to limit
abdominal aortic aneurysm (AAA) growth. Methods Data from animal model studies, human …

Systematic review and meta-analysis of interventions to slow progression of abdominal aortic aneurysm in mouse models

J Phie, S Thanigaimani, J Golledge - … , Thrombosis, and Vascular …, 2021 - Am Heart Assoc
Objective: There are no current effective abdominal aortic aneurysm (AAA) drug therapies.
An important limitation of most preclinical studies is that they test the effect of drugs on AAA …

Systematic review examining the association of angiotensin converting enzyme inhibitor and angiotensin receptor blocker prescription with abdominal aortic …

K Tian, S Thanigaimani, K Gibson… - European Journal of …, 2024 - Elsevier
Objective Whether angiotensin II blockade is an effective medical treatment for abdominal
aortic aneurysms (AAAs) has not been established. This systematic review and meta …

[HTML][HTML] The efficacy of pharmacotherapy for decreasing the expansion rate of abdominal aortic aneurysms: a systematic review and meta-analysis

I Guessous, D Periard, D Lorenzetti, J Cornuz… - PLoS …, 2008 - journals.plos.org
Background Pharmacotherapy may represent a potential means to limit the expansion rate
of abdominal aortic aneurysms (AAAs). Studies evaluating the efficacy of different …