Objective To study peripheral blood DNA differential methylation in oligozoospermic infertile
men in comparison with normozoospermic fertile controls. Design Case-control study …

STUDY QUESTION Do methylation changes in sperm DNA correlate with infertility? STUDY
ANSWER Loss of spermatogenesis and fertility was correlated with 1680 differentially …

Aberrant sperm DNA methylation patterns, mainly in imprinted genes, have been associated
with male subfertility and oligospermia. Here, we performed a genome‐wide methylation …

Abstract STUDY QUESTION Are there DNA methylation alterations in sperm that could
explain the reduced biological fertility of male partners from couples with unexplained …

Background DNA methylation analysis is useful for investigation of male fertility in mammals,
whereas the reliance on tissues limits the research on human. We have previously found the …

The objective of this study was to assess genome‐wide DNA methylation in testicular tissue
from azoospermic patients. A total of 94 azoospermic patients were recruited and classified …

Abstract Infertility affects 10–15% of couples, and approximately 50% of cases are linked to
male factor infertility. The purpose of this study was to evaluate the DNA methylation patterns …

BACKGROUND Studies in non-human mammals suggest that environmental factors can
influence spermatozoal DNA methylation, and some research suggests that spermatozoal …

The influence of aberrant sperm DNA methylation on the reproductive capacity of couples
has been postulated as a cause of infertility. This study compared the DNA methylation of …

Background Several studies have reported an association between male infertility and
aberrant sperm DNA methylation patterns, in particular in imprinted genes. In a recent …