One of the most widely used assisted reproductive technology (ART) is vitrification. The aim
of this study is to evaluate DNA methylation of H19/IGF2 differentially methylation region …

OBJECTIVE: To investigate the effects of embryo vitrification on the methylation status of the
H19/Igf2 differentially methylated domain (DMD) and the expression of those genes …

To explore the mechanisms leading to the poor quality of IVF blastocysts, the single-cell
whole-genome methylation sequencing technique was used in this study to analyse the …

Proper epigenetic modifications during preimplantation embryo development are important
for a successful pregnancy. We aim to investigate the putative influence of in vitro fertilization …

Vitrification is increasingly used in assisted reproductive technology (ART) laboratories
worldwide, and potential vitrification‐induced risks require further exploration. The effect of …

Objective To examine whether mouse oocytes vitrification could alter the deoxyribonucleic
acid (DNA) methylation of differentially methylated regions (DMRs) of three imprinted genes …

With the widespread application of embryo cryopreservation in assisted reproductive
techniques, it is necessary to assess the safety of long‐term cryopreservation of human …

Appropriate epigenetic changes in preimplantation embryos are critical for embryonic
development and successful pregnancy. The aim of this study was to evaluate the effects of …

Accurate reprogramming of DNA methylation occurring in preimplantation embryos is critical
for normal development of both fetus and placenta. Environmental stresses imposed on …

This study was conducted to investigate the pattern of DNA methylation in vitrified–thawed
mouse oocytes and their in vitro fertilized early embryos. Firstly, mouse oocytes at …