Cerebrovascular reactivity (CVR)-weighted blood-oxygenation-level-dependent magnetic
resonance imaging (BOLD-MRI) experiments are frequently used in conjunction with …

Blood oxygenation level-dependent (BOLD) or arterial spin labeling (ASL) MRI with
hypercapnic stimuli allow for measuring cerebrovascular reactivity (CVR). Hypercapnic …

Introduction: We aimed to demonstrate non-invasive measurements of regional oxygen
extraction fraction (OEF) from quantitative BOLD MRI modeling at baseline and after …

Characterizing the effect of oxygen (O2) modulation on the brain may provide a better
understanding of several clinically relevant problems, including acute mountain sickness …

Purpose The calibratable relationship between blood oxygenation (Y) and T2 allows
quantification of cerebral venous oxygenation. We aim to establish a calibration plot …

Noninvasive measurement of cerebral venous oxygenation can serve as a tool for better
understanding fMRI signals and for clinical evaluation of brain oxygen homeostasis. In this …

Background Oxygen extraction fraction (OEF) and cerebral metabolic rate of oxygen
(CMRO2) may serve as biomarkers in several diseases. OEF and CMRO2 can be estimated …

Normocapnic hyperoxic and hypercapnic hyperoxic gas challenges are increasingly being
used in cerebrovascular reactivity (CVR) and calibrated functional MRI experiments. The …

Abstract Purpose: To use T2′‐mapping together with Pulsed Arterial Spin Labeling (PASL)
providing quantitative information of deoxygenation level and cerebral blood flow (CBF) in …

Hypoxic hypoxia (inspiratory hypoxia) stimulates an increase in cerebral blood flow (CBF)
maintaining oxygen delivery to the brain. However, this response, particularly at the tissue …