Maternal high-fat diet during lactation reprograms the dopaminergic circuitry in mice

RN Lippert, S Hess, P Klemm… - The Journal of …, 2020 - Am Soc Clin Investig
The maternal perinatal environment modulates brain formation, and altered maternal
nutrition has been linked to the development of metabolic and psychiatric disorders in the …

Exposure to maternal high-fat diet induces extensive changes in the brain of adult offspring

DJ Fernandes, S Spring, AR Roy, LR Qiu, Y Yee… - Translational …, 2021 - nature.com
Maternal environmental exposures, such as high-fat diets, diabetes and obesity, can induce
long-term effects in offspring. These effects include increased risk of neurodevelopmental …

Maternal high fat diet alters offspring epigenetic regulators, amygdala glutamatergic profile and anxiety

KA Glendining, LC Fisher, CL Jasoni - Psychoneuroendocrinology, 2018 - Elsevier
Maternal obesity during pregnancy can impact long-term health, predisposition to disease,
and risk of neurological disorders in offspring. This may arise from disruption to epigenetic …

Maternal diet disrupts the placenta–brain axis in a sex-specific manner

AM Ceasrine, BA Devlin, JL Bolton, LA Green… - Nature …, 2022 - nature.com
High maternal weight is associated with detrimental outcomes in offspring, including
increased susceptibility to neurological disorders such as anxiety, depression and …

Maternal high‐fat diet and obesity impact palatable food intake and dopamine signaling in nonhuman primate offspring

HM Rivera, P Kievit, MA Kirigiti, LA Bauman… - …, 2015 - Wiley Online Library
Objective To utilize a nonhuman primate model to examine the impact of maternal high‐fat
diet (HFD) consumption and pre‐pregnancy obesity on offspring intake of palatable food …

Chronic consumption of a high-fat diet during pregnancy causes perturbations in the serotonergic system and increased anxiety-like behavior in nonhuman primate …

EL Sullivan, B Grayson, D Takahashi… - Journal of …, 2010 - Soc Neuroscience
Childhood obesity is associated with increased risk of behavioral/psychological disorders
including depression, anxiety, poor learning, and attention deficient disorder. As the majority …

Maternal overnutrition during critical developmental periods leads to different health adversities in the offspring: relevance of obesity, addiction and schizophrenia

G Sarker, K Litwan, R Kastli, D Peleg-Raibstein - Scientific reports, 2019 - nature.com
Maternal overnutrition during sensitive periods of early development increases the risk for
obesity and neuropsychiatric disorders later in life. However, it still remains unclear during …

The influence of maternal metabolic state and nutrition on offspring neurobehavioral development: a focus on preclinical models

AJ Mitchell, GA Dunn, EL Sullivan - Biological Psychiatry: Cognitive …, 2022 - Elsevier
The prevalence of both obesity and neurodevelopmental disorders has increased
substantially over the last several decades. Early environmental factors, including maternal …

Maternal high-fat intake alters presynaptic regulation of dopamine in the nucleus accumbens and increases motivation for fat rewards in the offspring

L Naef, L Moquin, G Dal Bo, B Giros, A Gratton… - Neuroscience, 2011 - Elsevier
High caloric intake during early postnatal development can have long term consequences
for the offspring. We previously reported that the adult offspring of dams fed a high-fat diet …

[HTML][HTML] Maternal dietary patterns are associated with susceptibility to a depressive-like phenotype in rat offspring

K Gawlińska, D Gawliński, M Korostyński… - Developmental …, 2021 - Elsevier
Environmental factors such as maternal diet, determine the pathologies that appear early in
life and can persist in adulthood. Maternally modified diets provided through pregnancy and …