Cytosine DNA methylation protects eukaryotic genomes by silencing transposons and
harmful DNAs, but also regulates gene expression during normal development. Loss of CG …

Plants use siRNAs to target cytosine DNA methylation to both symmetrical CG and
nonsymmetrical (CHG and CHH) sequence contexts. DNA methylation and siRNA clusters …

DNA methylation occurs in CG and non-CG sequence contexts. Non-CG methylation is
abundant in plants and is mediated by CHROMOMETHYLASE (CMT) and DOMAINS …

A contribution of DNA methylation to defense against invading nucleic acids and
maintenance of genome integrity is uncontested; however, our understanding of the extent …

DNA methylation is a conserved modification that must be precisely regulated during
development to facilitate its roles in silencing transposable elements and regulating gene …

DNA methylation plays a crucial role in suppressing mobilization of transposable elements
and regulation of gene expression. A number of studies have indicated that DNA …

Abstract DNA methylation (5-methylcytosine) in mammalian genomes predominantly occurs
at CpG dinucleotides, is maintained by DNA methyltransferase1 (Dnmt1), and is essential for …

DNA methylation has two essential roles in plants and animals—defending the genome
against transposons and regulating gene expression. Recent experiments in Arabidopsis …

De novo DNA methylation in Arabidopsis thaliana is catalyzed by the methyltransferase
DRM2, a homolog of the mammalian de novo methyltransferase DNMT3. DRM2 is targeted …

The CMT2 and RNA-directed DNA methylation (RdDM) pathways have been proposed to
separately maintain CHH methylation in specific regions of the Arabidopsis thaliana …