The impact of cigarette smoking can persist for extended periods following smoking
cessation and may involve epigenetic reprogramming. Changes in DNA methylation …

Background Multiple studies have made robust associations between differential DNA
methylation and exposure to cigarette smoke. But whether a DNA methylation phenotype is …

Background The evidence for epigenome-wide associations between smoking and DNA
methylation continues to grow through cross-sectional studies. However, few large-scale …

Aim: Epigenetic changes may occur in response to environmental stressors, and an altered
epigenome pattern may represent a stable signature of environmental exposure. Materials & …

Background: Smoking-associated DNA methylation levels identified through epigenome-
wide association studies (EWASs) are generally ascribed to smoking-reactive mechanisms …

Tobacco smoking is responsible for substantial morbidity and mortality worldwide, in
particular through cardiovascular, pulmonary, and malignant pathology. CpG methylation …

We conducted a genome-wide association study of blood DNA methylation and smoking,
attempted replication of previously discovered associations, and assessed the reversibility of …

Background—DNA methylation leaves a long-term signature of smoking exposure and is
one potential mechanism by which tobacco exposure predisposes to adverse health …

Cigarette smoking is an environmental risk factor for many chronic diseases, and disease
risk can often be managed by smoking control. Smoking can induce cellular and molecular …

Environmental factors such as tobacco smoking may have long-lasting effects on DNA
methylation patterns, which might lead to changes in gene expression and in a broader …