Background Trimethylamine‐N‐oxide (TMAO), a diet‐derived, gut microbial–host
cometabolite, has been associated with adverse cardiovascular outcomes in patient …

In recent years, a number of studies have alluded to the importance of the intestinal
microflora in controlling whole-body metabolic homeostasis and organ physiology. In …

ABSTRACT Background Trimethylamine N-oxide (TMAO), a diet-derived, gut microbial-host
cometabolite, has been linked to cardiometabolic diseases. However, the relations remain …

Objectives Recent metabolomic, experimental and clinical studies have demonstrated that
trimethylamine‐N‐oxide (TMAO), a microbiota‐dependent metabolite from dietary …

Trimethylamine N-oxide (TMAO) is a microbial metabolite derived from nutrients, such as
choline, L-carnitine, ergothioneine and betaine. Recently, it has come under the spotlight for …

The gut microbiota-dependent metabolite trimethylamine-N-oxide (TMAO) is linked to an
increased risk for cardiovascular diseases. Trimethylamine (TMA), which is subsequently …

Excessive consumption of diets high in sugars and saturated fat, frequently known as
western diet (WD), may lead to obesity and metabolic syndrome. Recent evidence shows …

Background Recent studies show a mechanistic link between gut microbiota-dependent
formation of the atherosclerosis-and thrombosis-promoting metabolite trimethylamine N …

Trimethylamine N-oxide (TMAO) is a gut microbiota metabolite derived from trimethylamine-
containing nutrient precursors such as choline, L-carnitine, and betaine, which are rich in …

Choline is metabolized by the gut microbiota into trimethylamine (TMA), the precursor of pro-
atherosclerotic molecule trimethylamine N-oxide (TMAO). A reduction in TMA formation has …