Gut microbiota-dependent marker TMAO in promoting cardiovascular disease: inflammation mechanism, clinical prognostic, and potential as a therapeutic target
S Yang, X Li, F Yang, R Zhao, X Pan, J Liang… - Frontiers in …, 2019 - frontiersin.org
Cardiovascular disease (CVD) is the leading cause of death worldwide, especially in
developed countries, and atherosclerosis (AS) is the common pathological basis of many …
developed countries, and atherosclerosis (AS) is the common pathological basis of many …
Increased Trimethylamine N-Oxide Portends High Mortality Risk Independent of Glycemic Control in Patients with Type 2 Diabetes Mellitus
BACKGROUND Recent studies show a mechanistic link between intestinal microbial
metabolism of dietary phosphatidylcholine and coronary artery disease pathogenesis …
metabolism of dietary phosphatidylcholine and coronary artery disease pathogenesis …
Plasma trimethylamine N-oxide and its metabolic precursors and risk of mortality, cardiovascular and renal disease in individuals with type 2-diabetes and albuminuria
SA Winther, JC Øllgaard, TW Hansen… - PLoS …, 2021 - journals.plos.org
Aims The trimethylamine N-oxide (TMAO) pathway is related to intestinal microbiota and has
been associated to risk of cardiovascular disease (CVD). We investigated associations …
been associated to risk of cardiovascular disease (CVD). We investigated associations …
Microbial trimethylamine-N-oxide as a disease marker: something fishy?
B Landfald, J Valeur, A Berstad… - Microbial ecology in health …, 2017 - Taylor & Francis
Production of trimethylamine-N-oxide (TMAO) via the gut microbiota has recently been
proposed as an important pathophysiological mechanism linking ingestion of 'unhealthy …
proposed as an important pathophysiological mechanism linking ingestion of 'unhealthy …
Circulating trimethylamine N-oxide is associated with increased risk of cardiovascular mortality in type-2 diabetes: Results from a Dutch Diabetes Cohort (ZODIAC-59)
JL Flores-Guerrero, PR van Dijk, MA Connelly… - Journal of Clinical …, 2021 - mdpi.com
Trimethylamine N-oxide (TMAO), a novel cardiovascular (CV) disease and mortality risk
marker, is a gut microbiota-derived metabolite as well. Recently, plasma concentrations of …
marker, is a gut microbiota-derived metabolite as well. Recently, plasma concentrations of …
Gut microbe-generated metabolite trimethylamine-N-oxide as cardiovascular risk biomarker: a systematic review and dose-response meta-analysis
GG Schiattarella, A Sannino, E Toscano… - European heart …, 2017 - academic.oup.com
Aims Gut microbiota-derived metabolite trimethylamine-N-oxide (TMAO) is emerging as a
new potentially important cause of increased cardiovascular risk. The purpose of this meta …
new potentially important cause of increased cardiovascular risk. The purpose of this meta …
A multi-omic association study of trimethylamine N-oxide
O Manor, N Zubair, MP Conomos, X Xu, JE Rohwer… - Cell reports, 2018 - cell.com
Trimethylamine N-oxide (TMAO) is a circulating metabolite that has been implicated in the
development of atherosclerosis and cardiovascular disease (CVD). In this paper, we identify …
development of atherosclerosis and cardiovascular disease (CVD). In this paper, we identify …
Trimethylamine N-oxide: a harmful, protective or diagnostic marker in lifestyle diseases?
A Nowiński, M Ufnal - Nutrition, 2018 - Elsevier
Diet has been considered a general health determinant for many years. Recent research
shows a connection between gut microbiota composition that is shaped by our diet and …
shows a connection between gut microbiota composition that is shaped by our diet and …
[HTML][HTML] Trimethylamine N-oxide (TMAO) is not associated with cardiometabolic phenotypes and inflammatory markers in children and adults
ABSTRACT Background Trimethylamine N-oxide (TMAO) is a diet-and microbiome-derived
metabolite and a proposed biomarker of adverse cardiometabolic outcomes. TMAO studies …
metabolite and a proposed biomarker of adverse cardiometabolic outcomes. TMAO studies …
Implications of the intestinal microbiota in diagnosing the progression of diabetes and the presence of cardiovascular complications
The prevalence of diabetes is steadily rising, and once it occurs, it can cause multiple
complications with a negative impact on the whole organism. Complications of diabetes may …
complications with a negative impact on the whole organism. Complications of diabetes may …