The development of a versatile biosensing platform to screen specific DNA sequences is still
an essential issue of molecular biology research and clinic diagnosis of genetic disease. In …

Breast cancer is one of the most commonly diagnosed cancers among females worldwide.
Early detection of breast cancer is of vital importance to the reduction of the mortality rate …

The detection of circulating tumor DNAs (ctDNAs) with high sensitivity plays an important
role in liquid biopsy diagnosis. For the detection of ctDNAs, we investigated the applicability …

Oncology detection technology is significant for the early detection of tumors. The current
study reports a new method that uses folate receptor (FR) as circulating tumor cells (CTCs) …

Diagnostic biomarkers based on epigenetic changes such as DNA methylation are
promising tools for early cancer diagnosis. However, there are significant difficulties in …

We report a method for the detection of target DNA through nicking endonuclease (NEase)-
assisted fluorescence resonance energy transfer (FRET) amplification. In this study, target …

Fluorescence resonance energy transfer (FRET) between fluorescein isothiocyanate (FITC)
and gold nanoparticles (Au NPs) is introduced in the lateral flow strip to detect cancer …

Transcription factors (TFs) are important cellular components that modulate gene
expression, and the malregulation of transcription will lead to a variety of diseases such as …

Many studies have confirmed that CYFRA21-1 is both a sensitive and specific marker for
non-small cell lung cancer (NSCLC), in particular, squamous cell carcinoma. Therefore …

We demonstrate the development of a new fluorescent biosensor for sensitive DNA
methylation assay by integrating single-molecule detection with endo IV-assisted signal …