Profiling genome-wide DNA methylation
DNA methylation is an epigenetic modification that plays an important role in regulating
gene expression and therefore a broad range of biological processes and diseases. DNA …
gene expression and therefore a broad range of biological processes and diseases. DNA …
Evaluation of bisulfite kits for DNA methylation profiling in terms of DNA fragmentation and DNA recovery using digital PCR
DNA methylation is one of the most important epigenetic modifications in the regulation of
gene transcription. The current gold standard to study this modification is bisulfite …
gene transcription. The current gold standard to study this modification is bisulfite …
Quantification of epigenetic biomarkers: an evaluation of established and emerging methods for DNA methylation analysis
N Redshaw, JF Huggett, MS Taylor, CA Foy… - BMC genomics, 2014 - Springer
Background DNA methylation is an important epigenetic mechanism in several human
diseases, most notably cancer. The quantitative analysis of DNA methylation patterns has …
diseases, most notably cancer. The quantitative analysis of DNA methylation patterns has …
MethVisual-visualization and exploratory statistical analysis of DNA methylation profiles from bisulfite sequencing
A Zackay, C Steinhoff - BMC research notes, 2010 - Springer
Background Exploration of DNA methylation and its impact on various regulatory
mechanisms has become a very active field of research. Simultaneously there is an arising …
mechanisms has become a very active field of research. Simultaneously there is an arising …
A survey of the approaches for identifying differential methylation using bisulfite sequencing data
DNA methylation is an important epigenetic mechanism that plays a crucial role in cellular
regulatory systems. Recent advancements in sequencing technologies now enable us to …
regulatory systems. Recent advancements in sequencing technologies now enable us to …
DNA methylation profiling using bisulfite-based epityping of pooled genomic DNA
DNA methylation plays a vital role in normal cellular function, with aberrant methylation
signatures being implicated in a growing number of human pathologies and complex human …
signatures being implicated in a growing number of human pathologies and complex human …
DNA methylation and cancer diagnosis
Y Delpu, P Cordelier, WC Cho, J Torrisani - International journal of …, 2013 - mdpi.com
DNA methylation is a major epigenetic modification that is strongly involved in the
physiological control of genome expression. DNA methylation patterns are largely modified …
physiological control of genome expression. DNA methylation patterns are largely modified …
Quantitative DNA methylation analysis: the promise of high-throughput epigenomic diagnostic testing in human neoplastic disease
WB Coleman, AG Rivenbark - The Journal of Molecular Diagnostics, 2006 - jmdjournal.org
The term “epigenetics” was first introduced by Conrad Waddington in 1942 to describe “the
interactions of genes with their environment, which bring the phenotype into being.” 1 Later …
interactions of genes with their environment, which bring the phenotype into being.” 1 Later …
Profiling DNA methylation based on next-generation sequencing approaches: new insights and clinical applications
D Barros-Silva, CJ Marques, R Henrique, C Jerónimo - Genes, 2018 - mdpi.com
DNA methylation is an epigenetic modification that plays a pivotal role in regulating gene
expression and, consequently, influences a wide variety of biological processes and …
expression and, consequently, influences a wide variety of biological processes and …
[图书][B] DNA methylation
J Tost - 2009 - Springer
Epigenetics can be defined as the study of heritable changes in gene expression without
alteration of the DNA sequence itself. This means that epigenetic variants are stable …
alteration of the DNA sequence itself. This means that epigenetic variants are stable …