Self‐renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phase

KA Becker, PN Ghule, JA Therrien… - Journal of cellular …, 2006 - Wiley Online Library
Competency for self‐renewal of human embryonic stem (ES) cells is linked to pluripotency.
However, there is a critical paucity of fundamental parameters of human ES cell division. In …

Molecular mechanisms involved in self‐renewal and pluripotency of embryonic stem cells

N Liu, M Lu, X Tian, Z Han - Journal of cellular physiology, 2007 - Wiley Online Library
Embryonic stem cells (ES cells) are derived from inner cell mass (ICM). The self‐renewal
and pluripotency are the main specificities of ES cells, which are likely to reveal a deeper …

Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture

M Amit, MK Carpenter, MS Inokuma, CP Chiu… - Developmental …, 2000 - Elsevier
Embryonic stem (ES) cell lines derived from human blastocysts have the developmental
potential to form derivatives of all three embryonic germ layers even after prolonged culture …

The regulation of self-renewal in human embryonic stem cells

S Avery, K Inniss, H Moore - Stem cells and development, 2006 - liebertpub.com
Human embryonic stem (hES) cells have the ability to self-renew while maintaining their
pluripotency. The ability of stem cells to self-renew expansively is essential in both …

A high proliferation rate is required for cell reprogramming and maintenance of human embryonic stem cell identity

S Ruiz, AD Panopoulos, A Herrerías, KD Bissig, M Lutz… - Current Biology, 2011 - cell.com
Human embryonic stem (hES) cells show an atypical cell-cycle regulation characterized by a
high proliferation rate and a short G1 phase [1, 2]. In fact, a shortened G1 phase might …

Analysis of the cell cycle in mouse embryonic stem cells

P Savatier, H Lapillonne, L Jirmanova, L Vitelli… - Embryonic Stem Cells …, 2002 - Springer
The molecular mechanisms underlying self-renewal of pluripotent embryonic stem (ES) cells
is still poorly understood. Deciphering these mechanisms is of prime importance for at least …

Mechanisms of self-renewal in human embryonic stem cells

R Stewart, M Stojkovic, M Lako - European Journal of Cancer, 2006 - Elsevier
Embryonic stem cells (ESCs) are the pluripotent cell population derived from the inner cell
mass of pre-implantation embryos and are characterised by prolonged self-renewal and the …

[HTML][HTML] Conserved and divergent paths that regulate self-renewal in mouse and human embryonic stem cells

M Rao - Developmental biology, 2004 - Elsevier
The past few years have seen remarkable progress in our understanding of embryonic stem
cell (ES cell) biology. The necessity of examining human ES cells in culture, coupled with …

Human embryonic stem cells

MF Pera, B Reubinoff, A Trounson - Journal of cell science, 2000 - journals.biologists.com
Embryonic stem (ES) cells are cells derived from the early embryo that can be propagated
indefinitely in the primitive undifferentiated state while remaining pluripotent; they share …

Embryonic stem cells

A Biswas, R Hutchins - Stem cells and development, 2007 - liebertpub.com
Stem cells are unique cell populations with the ability to choose between self-renewal and
differentiation. Embryonic stem (ES) cells have the ability to form any fully differentiated cell …