recountmethylation enables flexible analysis of public blood DNA methylation array data
Thousands of DNA methylation (DNAm) array samples from human blood are publicly
available on the Gene Expression Omnibus (GEO), but they remain underutilized for …
available on the Gene Expression Omnibus (GEO), but they remain underutilized for …
GLINT: a user-friendly toolset for the analysis of high-throughput DNA-methylation array data
GLINT is a user-friendly command-line toolset for fast analysis of genome-wide DNA
methylation data generated using the Illumina human methylation arrays. GLINT, which …
methylation data generated using the Illumina human methylation arrays. GLINT, which …
CoMeBack: DNA methylation array data analysis for co-methylated regions
Motivation High-dimensional DNA methylation (DNAm) array coverage, while sparse in the
context of the entire DNA methylome, still constitutes a very large number of CpG probes …
context of the entire DNA methylome, still constitutes a very large number of CpG probes …
GMQN: A reference-based method for correcting batch effects as well as probes bias in HumanMethylation BeadChip
Abstract Illumina HumanMethylation BeadChip is one of the most cost-effective ways to
quantify DNA methylation levels at the single-base level across the human genome, which …
quantify DNA methylation levels at the single-base level across the human genome, which …
GMQN: a reference-based method for correcting batch effects and probe bias in humanmethylation beadchip
The Illumina HumanMethylation BeadChip is one of the most cost-effective methods to
quantify DNA methylation levels at single-base resolution across the human genome, which …
quantify DNA methylation levels at single-base resolution across the human genome, which …
Meffil: efficient normalisation and analysis of very large DNA methylation samples
Background Technological advances in high throughput DNA methylation microarrays have
allowed dramatic growth of a new branch of epigenetic epidemiology. DNA methylation …
allowed dramatic growth of a new branch of epigenetic epidemiology. DNA methylation …
EWAS Data Hub: a resource of DNA methylation array data and metadata
Abstract Epigenome-Wide Association Study (EWAS) has become an effective strategy to
explore epigenetic basis of complex traits. Over the past decade, a large amount of …
explore epigenetic basis of complex traits. Over the past decade, a large amount of …
Comparison of methylation capture sequencing and Infinium MethylationEPIC array in peripheral blood mononuclear cells
Background Epigenome-wide association studies (EWAS) have been widely applied to
identify methylation CpG sites associated with human disease. To date, the Infinium …
identify methylation CpG sites associated with human disease. To date, the Infinium …
methylCC: technology-independent estimation of cell type composition using differentially methylated regions
SC Hicks, RA Irizarry - Genome biology, 2019 - Springer
A major challenge in the analysis of DNA methylation (DNAm) data is variability introduced
from intra-sample cellular heterogeneity, such as whole blood which is a convolution of …
from intra-sample cellular heterogeneity, such as whole blood which is a convolution of …
Adjustment of cell-type composition minimizes systematic bias in blood DNA methylation profiles derived by DNA collection protocols
Differences in DNA collection protocols may be a potential confounder in epigenome-wide
association studies (EWAS) using a large number of blood specimens from multiple …
association studies (EWAS) using a large number of blood specimens from multiple …