Few studies had investigated genome-wide methylation in glioblastoma multiforme (GBM).
Our goals were to study differential methylation across the genome in gene promoters using …

Glioblastoma multiforme (GBM) is the most frequent and devastating primary brain tumor in
adults. The presence of epigenetic lesions, like hypermethylation of known tumor …

Objective: To identify a specific hypermethylated molecular biomarker for human malignant
glioblastoma prognosis. Materials and Methods: Genome-wide methylation profiling was …

Glioblastoma multiforme (GBM) is one of the most lethal and damaging types of human
cancer. The current study was conducted to identify differentially methylated genes (DMGs) …

Differentially methylated genes (DMGs) serve a crucial role in the pathogenesis of glioma
via the regulation of the cell cycle, proliferation, apoptosis, migration, infiltration, DNA repair …

Glioblastoma multiforme (GBM) is the most malignant primary tumour type of the central
nervous system with limited therapeutic options and poor prognosis, and its pathogenic …

Background Changes in promoter DNA methylation pattern of genes involved in key
biological pathways have been reported in glioblastoma. Genome-wide assessments of …

Different gene expression and methylation profiles are identified in glioblastoma (GBM). To
screen the differentially expressed genes affected by DNA methylation modification and …

Aberrant DNA hypomethylation may play an important role in the growth rate of glioblastoma
(GBM), but the functional impact on transcription remains poorly understood. We assayed …

Neuroblastoma is a very heterogeneous tumor of childhood. The clinical spectra range from
very aggressive metastatic disease to spontaneous regression, even without therapy …