Background DNA methylation is an important epigenetic mark that can potentially link early
life exposures to adverse health outcomes later in life. Host factors like sex and age strongly …

Epigenetic processes play a key role in orchestrating transcriptional regulation during
development. The importance of DNA methylation in fetal brain development is highlighted …

Background Among children, sex-specific differences in disease prevalence, age of onset,
and susceptibility have been observed in health conditions including asthma, immune …

DNA methylation (DNAm) is known to play a pivotal role in childhood health and
development, but a comprehensive characterization of genome-wide DNAm trajectories …

Prenatal development and early childhood are critical periods for establishing the tissue-
specific epigenome, and may have a profound impact on health and disease in later life …

Cytosine-5 methylation within CpG dinucleotides is a potentially important mechanism of
epigenetic influence on human traits and disease. In addition to influences of age and …

Background Preterm birth and shorter duration of pregnancy are associated with increased
morbidity in neonatal and later life. As the epigenome is known to have an important role …

Analysis of DNA methylation helps to understand the effects of environmental exposures as
well as the role of epigenetics in human health. Illumina, Inc. recently replaced the …

DNA methylation changes have been implicated in many common chronic diseases leading
to the hypothesis that environmental and age-related DNA methylation changes within …

DNA methylation (DNAm) plays diverse roles in human biology, but this dynamic epigenetic
mark remains far from fully characterized. Although earlier studies uncovered loci that …