Fluoroquinolones increase susceptibility to aortic aneurysm and aortic dissection: Molecular mechanism and clinical evidence

X Xuan, Y Li, G Cao, R Zhang, J Hu, H Jin… - Vascular …, 2023 - journals.sagepub.com
Aortic aneurysm (AA) and aortic dissection (AD) are prevalent severe cardiovascular
diseases that result in catastrophic complications and unexpected deaths. Owing to the lack …

[HTML][HTML] Do fluoroquinolones increase aortic aneurysm or dissection incidence and mortality? A systematic review and meta-analysis

C Chen, B Patterson, R Simpson, Y Li… - Frontiers in …, 2022 - frontiersin.org
Objective The aim of this study was to determine the association between fluoroquinolones
(FQs) use, the risk of de novo aortic aneurysm or dissection (AAD), and the prognosis of …

[HTML][HTML] Current progress of fluoroquinolones-increased risk of aortic aneurysm and dissection

C Jun, B Fang - BMC cardiovascular disorders, 2021 - Springer
Aortic aneurysm (AA) and aortic dissection (AD) are major life-threatening diseases around
the world. AA is a localized or diffuse dilation of the aorta, while AD is the separation of the …

[HTML][HTML] The association between fluoroquinolones and aortic dissection and aortic aneurysms: a systematic review and meta-analysis

I Wee, B Chin, N Syn, KS Lee, JJ Ng, AMTL Choong - Scientific reports, 2021 - nature.com
Previous studies have drawn causal associations between fluoroquinolone use and
collagen pathologies including tendon rupture and retinopathy. This meta-analysis …

Fluoroquinolones are associated with increased risk of aortic aneurysm or dissection: systematic review and meta-analysis

NV Ribeiro, RG Melo, NC Guerra, Â Nobre… - Seminars in Thoracic …, 2021 - Elsevier
Fluoroquinolone use has been associated with collagen disease events, raising safety
concerns. We hypothesized that the use of fluoroquinolones is associated with aortic …

Effects of fluoroquinolones on outcomes of patients with aortic dissection or aneurysm

SW Chen, YH Chan, V Chien-Chia Wu… - Journal of the American …, 2021 - jacc.org
Background Recent population-based studies have revealed that the use of
fluoroquinolones (FQs) is associated with an increased risk of aortic dissection (AD) and …

Lack of association between fluoroquinolone and aortic aneurysm or dissection

K Huh, M Kang, J Jung - European Heart Journal, 2023 - academic.oup.com
Abstract Background and Aims An increased risk of aortic aneurysm and aortic dissection
(AA/AD) has been reported with fluoroquinolone (FQ) use. However, recent studies …

Fluoroquinolones and the risk of aortic aneurysm or aortic dissection: a systematic review and meta-analysis

P Rawla, ML El Helou… - … & Hematological Agents …, 2019 - ingentaconnect.com
Objectives: We performed a systematic review and meta-analysis to explore the risk of an
aortic aneurysm or aortic dissection following fluoroquinolone administration. Methods …

[HTML][HTML] The association between the risk of aortic aneurysm/aortic dissection and the use of fluroquinolones: A systematic review and meta-analysis

CC Lai, YH Wang, KH Chen, CH Chen, CY Wang - Antibiotics, 2021 - mdpi.com
This study aimed to investigate the association between the risk of aortic aneurysm
(AA)/aortic dissection (AD) and the use of fluoroquinolones (FQs). PubMed, Embase …

Assessing fluoroquinolone‐associated aortic aneurysm and dissection: Data mining of the public version of the FDA adverse event reporting system

L Meng, J Huang, Y Jia, H Huang… - International journal of …, 2019 - Wiley Online Library
Aims A recent large epidemiological study found fluoroquinolone use is associated with an
increased risk of aortic aneurysm or dissection. We aimed to examine fluoroquinolone …