Current management of aortic aneurysms relies exclusively on prophylactic operative repair
of larger aneurysms. Great potential exists for successful medical therapy that halts or …

Aortic aneurysm is a permanent focal dilation of the aorta. It is usually an asymptomatic
disease but can lead to sudden death due to aortic rupture. Aortic aneurysm-related …

Thoracic aortic aneurysms that progress to acute aortic dissections are often fatal. Thoracic
aneurysms have been managed with treatment with β-adrenergic blocking agents (β …

About 20% of individuals afflicted with thoracic aortic disease have single-gene mutations
that predispose the vessel to aneurysm formation and/or acute aortic dissection often without …

OBJECTIVE: Losartan potassium (INN losartan), an antihypertensive drug, has been shown
to prevent thoracic aortic aneurysm in Marfan syndrome through the inhibition of …

Thoracic aortic aneurysms can be triggered by genetic disorders such as Marfan syndrome
(MFS) and related aortic diseases as well as by inflammatory disorders such as giant cell …

Aortic aneurysm is a chronic aortic disease affected by many factors. Although it is generally
asymptomatic, it poses a significant threat to human life due to a high risk of rupture …

Importance Thoracic aortic aneurysms leading to acute aortic dissections are a major cause
of morbidity and mortality despite significant advances in surgical treatment, which remains …

Abdominal aortic aneurysms (AAAs) are an increasingly common and potentially lethal
condition. Surgical repair of AAA is now yet performed quite safely, yet ruptured AAAs still …

Abdominal aortic aneurysms (AAAs) are a common but asymptomatic disease that has high
susceptibility to rupture. Current therapeutic options are limited to surgical procedures …