Phagocytosis by innate immune cells is an important process for protection against multiple
pathologies and is particularly important for resistance to infection. However, phagocytosis …

The cell walls and capsules of Cryptococcus neoformans, a yeast-type fungal pathogen, are
rich in polysaccharides. Dectin-2 is a C-type lectin receptor (CLR) that recognizes high …

C-type lectin receptors (CLRs) are diverse, trans-membrane proteins that function as pattern
recognition receptors (PRRs) which are necessary for orchestrating immune responses …

Cryptococcus gattii is a capsular fungal pathogen, which causes life-threatening
cryptococcosis in immunocompetent individuals. This emerging pathogen is less likely to be …

Dectin-2 is a C-type lectin receptor that recognizes high mannose polysaccharides.
Cryptococcus neoformans, a yeast-form fungal pathogen, is rich in polysaccharides in its cell …

We have re-investigated the role of the complement system and the non-opsonic pattern
recognition receptors dectin-1 and dectin-2 in the recognition of fungal particles by …

Antigen presenting cells recognize pathogens via pattern recognition receptors (PRR),
which upon ligation transduce intracellular signals that can induce innate immune …

The pathogenic fungus Cryptococcus enters the human host via inhalation into the lung and
is able to reside in a niche environment that is serum-(opsonin) limiting. Little is known about …

C-type lectin receptors (CLRs) play critical roles as pattern-recognition receptors (PRRs) for
sensing Candida albicans infection, which can be life-threatening for immunocompromised …

The innate recognition of fungal pathogens is mediated by a variety of pattern recognition
receptors (PRRs), although much interest has focussed on the Toll-like Receptors (TLR) …