Lineages derived from Cryptococcus neoformans type strain H99 support a link between the capacity to be pleomorphic and virulence
The pathogenic yeast Cryptococcus neoformans causes nearly 200,000 deaths annually in
immunocompromised individuals. Cryptococcus cells can undergo substantial …
immunocompromised individuals. Cryptococcus cells can undergo substantial …
[HTML][HTML] Convergent microevolution of Cryptococcus neoformans hypervirulence in the laboratory and the clinic
Reference strains are a key component of laboratory research, providing a common
background allowing for comparisons across a community of researchers. However …
background allowing for comparisons across a community of researchers. However …
The interplay of phenotype and genotype in Cryptococcus neoformans disease
S Altamirano, KM Jackson, K Nielsen - Bioscience Reports, 2020 - portlandpress.com
Cryptococcus neoformans is an opportunistic fungal pathogen that causes life-threatening
meningitis primarily in immunocompromised individuals. In order to survive and proliferate …
meningitis primarily in immunocompromised individuals. In order to survive and proliferate …
Microevolution of Serial Clinical Isolates of Cryptococcus neoformans var. grubii and C. gattii
The pathogenic species of Cryptococcus are a major cause of mortality owing to severe
infections in immunocompromised as well as immunocompetent individuals. Although …
infections in immunocompromised as well as immunocompetent individuals. Although …
Microevolution of a Standard Strain ofCryptococcus neoformans Resulting in Differences in Virulence and Other Phenotypes
SP Franzot, J Mukherjee, R Cherniak… - Infection and …, 1998 - Am Soc Microbiol
Cryptococcus neoformans is a major fungal pathogen for patients with debilitated immune
systems. However, no information is available on the stability of virulence or of phenotypes …
systems. However, no information is available on the stability of virulence or of phenotypes …
[HTML][HTML] Phenotypic switching in Cryptococcus neoformans
BC Fries, DL Goldman, A Casadevall - Microbes and infection, 2002 - Elsevier
Cryptococcus neoformans strains exhibit considerable phenotype variability with regards to
the capsular polysaccharide, sterol composition of the cell wall, and cell and colony …
the capsular polysaccharide, sterol composition of the cell wall, and cell and colony …
A Unique Chromosomal Rearrangement in the Cryptococcus neoformans var. grubii Type Strain Enhances Key Phenotypes Associated with Virulence
CA Morrow, IR Lee, EWL Chow, KL Ormerod… - MBio, 2012 - Am Soc Microbiol
The accumulation of genomic structural variation between closely related populations over
time can lead to reproductive isolation and speciation. The fungal pathogen Cryptococcus is …
time can lead to reproductive isolation and speciation. The fungal pathogen Cryptococcus is …
Interaction Between Genetic Background and the Mating-Type Locus in Cryptococcus neoformans Virulence Potential
The study of quantitative traits provides a window on the interactions between multiple
unlinked genetic loci. The interaction between hosts and pathogenic microbes, such as …
unlinked genetic loci. The interaction between hosts and pathogenic microbes, such as …
It's not all about us: evolution and maintenance of Cryptococcus virulence requires selection outside the human host
AC Gerstein, K Nielsen - Yeast, 2017 - Wiley Online Library
Cryptococcus is predominantly an AIDS‐related pathogen that causes significant morbidity
and mortality in immunocompromised patients. Research studies have historically focused …
and mortality in immunocompromised patients. Research studies have historically focused …
[PDF][PDF] Microevolution of serial clinical isolates of Cryptococcus neoformans var. grubii and C. gattii. mBio 8: e00166-17
Y Chen, RA Farrer, C Giamberardino, S Sakthikumar… - 2017 - dukespace.lib.duke.edu
The pathogenic species of Cryptococcus are a major cause of mortality owing to severe
infections in immunocompromised as well as immunocompetent individuals. Although …
infections in immunocompromised as well as immunocompetent individuals. Although …