ROM2 is associated with Cryptococcus neoformans virulence. We examined additional roles
of ROM2 in C. neoformans and found that ROM2 plays a role in several cell functions …

Cryptococcus neoformans is an encapsulated opportunistic organism that can undergo
phenotypic switching. In this process, the parent smooth colony (SM) switches to a more …

Phenotypic switching has been linked to the virulence of many pathogens, including fungi.
However, it has not been conclusively shown to occur in vivo or to influence the outcome of …

The human pathogen Cryptococcus neoformans causes meningo-encephalitis. The
polysaccharide capsule is an important virulence factor for this yeast-like fungus. Previously …

Cryptococcus neoformans capsule structure modifications after prolonged in vitro growth or
in vivo passaging have been reported previously. However, nothing is known about the …

The opportunistic fungal pathogen Cryptococcus neoformans is a leading cause of mortality
among the human immunodeficiency virus/acquired immunodeficiency syndrome …

Cryptococcus neoformans is an unconventional dimorphic fungus that can grow either as a
yeast or in a filamentous form. To facilitate investigation of genetic factors important for its …

The ability of fungi to transition between unicellular and multicellular growth has a profound
impact on our health and the economy. Many important fungal pathogens of humans …

A pet cockatoo was the suspected source of Cryptococcus neoformans recovered from an
immunocompromised patient with cryptococcosis based on molecular analyses available in …

The polysaccharide capsule is one of the established virulence factors in Cryptococcus
neoformans that provides a barrier against the host-mediated immune response. Mutation of …