A multi-host approach was followed to screen a library of 1201 signature-tagged deletion
strains of Cryptococcus neoformans mutants to identify previously unknown virulence …

The human fungal pathogen Cryptococcus neoformans is able to rapidly and effectively
adapt to varying conditions, favoring its survival in the environment and in the infected host …

Cryptococcus neoformans is a human fungal pathogen that causes lethal infections of the
lung and central nervous system in immunocompromised individuals. C. neoformans has a …

Background The adaptation of pathogenic fungi to the host environment via large-scale
genomic changes is a poorly characterized phenomenon. Cryptococcus neoformans is the …

Environmental pathogens move from ecological niches to mammalian hosts, requiring
adaptation to dramatically different environments. Microbes that disseminate farther …

The phenotypic plasticity of Cryptococcus neoformans is widely studied and demonstrated in
vitro, but its influence on pathogenicity remains unclear. In this study, we investigated the …

Cryptococcus neoformans is a pathogenic basidiomycetous yeast responsible for more than
600,000 deaths each year. It occurs as two serotypes (A and D) representing two varieties …

Cryptococcosis is caused by the opportunistic pathogen Cryptococcus neoformans or by the
primary pathogen Cryptococcus gattii. Epidemiological studies suggest that patients infected …

Cryptococcus neoformans is the major causative agent of fungal meningoencephalitis in
both immunocompromised and immunocompetent individuals. During infection, this fungus …

Cryptococcus neoformans (CN), an encapsulated, ubiquitous environmental yeast, is
pathogenic for humans, primarily those with compromised immune function. CN is believed …