Cryptococcus neoformans STE12α Regulates Virulence but Is Not Essential for Mating

YC Chang, BL Wickes, GF Miller, LA Penoyer… - The Journal of …, 2000 - rupress.org
The Cryptococcus neoformans STE12 α gene, a homologue of Saccharomyces cerevisiae
STE12, exists only in mating type (MAT) α cells. In S. cerevisiae, STE12 was required for …

Cryptococcus gattii isolates from the British Columbia cryptococcosis outbreak induce less protective inflammation in a murine model of infection than Cryptococcus …

PY Cheng, A Sham, JW Kronstad - Infection and immunity, 2009 - Am Soc Microbiol
The fungal pathogen Cryptococcus neoformans causes approximately one million cases of
cryptococcosis per year in people with AIDS. In contrast, the related species C. gattii is …

Isolation, Characterization, and Localization of a Capsule-Associated Gene, CAP10, of Cryptococcus neoformans

YC Chang, KJ Kwon-Chung - Journal of bacteriology, 1999 - Am Soc Microbiol
Cryptococcus neoformans is a pathogenic fungus which most commonly affects the central
nervous system and causes fatal meningoencephalitis primarily in patients with AIDS. This …

[HTML][HTML] Associations between Cryptococcus Genotypes, Phenotypes, and Clinical Parameters of Human Disease: A Review

MC Montoya, PM Magwene, JR Perfect - Journal of Fungi, 2021 - mdpi.com
The genus Cryptococcus contains two primary species complexes that are significant
opportunistic human fungal pathogens: C. neoformans and C. gattii. In humans …

Phenotypic switching of Cryptococcus neoformans can influence the outcome of the human immune response

D Pietrella, B Fries, P Lupo, F Bistoni… - Cellular …, 2003 - Wiley Online Library
The human pathogenic fungus Cryptococcus neoformans exhibits the phenomenon of
phenotypic switching, a process that generates variant colonies that can differ in …

Dynamic changes in the morphology of Cryptococcus neoformans during murine pulmonary infection

M Feldmesser, Y Kress, A Casadevall - Microbiology, 2001 - microbiologyresearch.org
The pathogenesis of Cryptococcus neoformans infection has been studied extensively with
respect to inflammatory and pathological changes, but very little information is available …

Specialization of the HOG Pathway and Its Impact on Differentiation and Virulence of Cryptococcus neoformans

YS Bahn, K Kojima, GM Cox… - Molecular biology of the …, 2005 - Am Soc Cell Biol
The human pathogenic fungus Cryptococcus neoformans has diverged from a common
ancestor into three biologically distinct varieties or sibling species over the past 10–40 …

Cryptococcus neoformans host adaptation: toward biological evidence of dormancy

A Alanio, F Vernel-Pauillac, A Sturny-Leclère, F Dromer - MBio, 2015 - Am Soc Microbiol
Cryptococcosis is an opportunistic infection due to the ubiquitous yeast Cryptococcus
neoformans. This yeast interacts closely with innate immune cells, leading to various fates …

[HTML][HTML] Updated View of Cryptococcus neoformans Mating Type and Virulence

AP Mitchell - Infection and immunity, 2003 - Am Soc Microbiol
A paper by Nielsen et al. in this issue of Infection and Immunity (5) will have significant
impact on the study of Cryptococcus neoformans, an opportunistic fungal pathogen that …

Comparative Analysis of Environmental and Clinical Populations of Cryptococcus neoformans

AP Litvintseva, L Kestenbaum, R Vilgalys… - Journal of clinical …, 2005 - Am Soc Microbiol
Cryptococcus neoformans is a major, global cause of meningoencephalitis in
immunocompromised patients. Despite advances in the molecular epidemiology of C …