A high-throughput DNA methylation analysis of a single cell
M Kantlehner, R Kirchner, P Hartmann… - Nucleic acids …, 2011 - academic.oup.com
In recent years, the field of epigenetics has grown dramatically and has become one of the
most dynamic and fast-growing branches of molecular biology. The amount of diseases …
most dynamic and fast-growing branches of molecular biology. The amount of diseases …
Introduction to single-cell DNA methylation profiling methods
J Ahn, S Heo, J Lee, D Bang - Biomolecules, 2021 - mdpi.com
DNA methylation is an epigenetic mechanism that is related to mammalian cellular
differentiation, gene expression regulation, and disease. In several studies, DNA …
differentiation, gene expression regulation, and disease. In several studies, DNA …
Analysis of epigenetic modifications of DNA in human cells
LS Kristensen, MB Treppendahl… - Current protocols in …, 2013 - Wiley Online Library
Epigenetics, the study of somatically heritable changes in gene expression not related to
changes in the DNA sequence, is a rapidly expanding research field that plays important …
changes in the DNA sequence, is a rapidly expanding research field that plays important …
Considerations for design and analysis of DNA methylation studies
KB Michels, AM Binder - DNA Methylation Protocols, 2018 - Springer
The number of epigenetic studies is exponentially increasing. There is anticipation that DNA
methylation may close gaps in our understanding of disease etiology, and how certain risk …
methylation may close gaps in our understanding of disease etiology, and how certain risk …
DNA methylation data analysis and its application to cancer research
With the rapid development of genome-wide high-throughput technologies, including
expression arrays, SNP arrays and next-generation sequencing platforms, enormous …
expression arrays, SNP arrays and next-generation sequencing platforms, enormous …
The application of next generation sequencing in DNA methylation analysis
Y Zhang, A Jeltsch - Genes, 2010 - mdpi.com
DNA methylation is a major form of epigenetic modification and plays essential roles in
physiology and disease processes. In the human genome, about 80% of cytosines in the 56 …
physiology and disease processes. In the human genome, about 80% of cytosines in the 56 …
DNA methylation analysis: choosing the right method
S Kurdyukov, M Bullock - Biology, 2016 - mdpi.com
In the burgeoning field of epigenetics, there are several methods available to determine the
methylation status of DNA samples. However, choosing the method that is best suited to …
methylation status of DNA samples. However, choosing the method that is best suited to …
Single-cell DNA methylation profiling: technologies and biological applications
ID Karemaker, M Vermeulen - Trends in biotechnology, 2018 - cell.com
DNA methylation is an epigenetic modification that plays an important role in gene
expression regulation, development, and disease. Recent technological innovations have …
expression regulation, development, and disease. Recent technological innovations have …
[图书][B] DNA methylation
J Tost - 2009 - Springer
Epigenetics can be defined as the study of heritable changes in gene expression without
alteration of the DNA sequence itself. This means that epigenetic variants are stable …
alteration of the DNA sequence itself. This means that epigenetic variants are stable …
Variations in DNA methylation patterns during the cell cycle of HeLa cells
SE Brown, MF Fraga, ICG Weaver, M Berdasco… - Epigenetics, 2007 - Taylor & Francis
DNA methylation has been viewed as a stable component of the epigenome, which is
established during development and fixed thereafter. We show here using nearest neighbor …
established during development and fixed thereafter. We show here using nearest neighbor …