[HTML][HTML] Loss of DIP2C in RKO cells stimulates changes in DNA methylation and epithelial-mesenchymal transition
C Larsson, MA Ali, T Pandzic, AM Lindroth, L He… - BMC cancer, 2017 - Springer
Background The disco-interacting protein 2 homolog C (DIP2C) gene is an uncharacterized
gene found mutated in a subset of breast and lung cancers. To understand the role of DIP2C …
gene found mutated in a subset of breast and lung cancers. To understand the role of DIP2C …
Heterozygous loss of Dip2B enhances tumor growth and metastasis by altering immune microenvironment
Cancer is caused by abnormal cell growth and metastasis to other tissues. Development of
cancers is complex and underlining mechanisms are mostly unknown. Disco-interacting …
cancers is complex and underlining mechanisms are mostly unknown. Disco-interacting …
DIP2C expression in breast cancer and its clinical significance
J Li, JL Ping, B Ma, YR Chen, LQ Li - Pathology-Research and Practice, 2017 - Elsevier
Introduction The aim of this study was to investigate DIP2C expression in different subtypes
of breast cancer tissues and cell lines and its correlation with clinicopathologic and …
of breast cancer tissues and cell lines and its correlation with clinicopathologic and …
[HTML][HTML] Lysine demethylase 2A expression in cancer-associated fibroblasts promotes breast tumour growth
JY Chen, CF Li, YS Lai, WC Hung - British Journal of Cancer, 2021 - nature.com
Background Our previous study demonstrated that lysine demethylase 2A (KDM2A)
enhances stemness in breast cancer cells. This demethylase is also highly expressed in …
enhances stemness in breast cancer cells. This demethylase is also highly expressed in …
Histone demethylase KDM7A is required for stem cell maintenance and apoptosis inhibition in breast cancer
Z Meng, Y Liu, J Wang, H Fan, H Fang… - Journal of Cellular …, 2020 - Wiley Online Library
Histone demethylase KDM7A regulates neuronal differentiation and development in
mammals. In this study, we found that KDM7A was also required for breast cancer stem cells …
mammals. In this study, we found that KDM7A was also required for breast cancer stem cells …
Lysine demethylase KDM3A regulates breast cancer cell invasion and apoptosis by targeting histone and the non-histone protein p53
Invasive growth and apoptosis resistance of breast cancer cells are associated with
metastasis and disease relapse. Here we identified that the lysine-specific demethylase …
metastasis and disease relapse. Here we identified that the lysine-specific demethylase …
[HTML][HTML] Genome-wide DNA methylation analysis of breast cancer MCF-7/Taxol cells with MeDIP-Seq
Y Shi, W Gong, X Gong, P Wang, X Zhao - PloS one, 2020 - journals.plos.org
Breast cancer (BC) is the most frequently diagnosed tumor in women worldwide. Although
the combination of surgery and Taxol chemotherapy can achieve a certain therapeutic effect …
the combination of surgery and Taxol chemotherapy can achieve a certain therapeutic effect …
Loss of desmocollin 1-3 and homeobox genes PITX1 and CDX2 are associated with tumor progression and survival in colorectal carcinoma
T Knösel, Y Chen, S Hotovy, U Settmacher… - International journal of …, 2012 - Springer
Background Genomewide expression profiling has identified a number of genes
differentially expressed in colorectal carcinomas (CRCs) compared to normal tissue. Some …
differentially expressed in colorectal carcinomas (CRCs) compared to normal tissue. Some …
[HTML][HTML] Expression patterns and potential biological roles of Dip2a
Disconnected (disco)-interacting protein 2 homolog A is a member of the DIP2 protein family
encoded by Dip2a gene. Dip2a expression pattern has never been systematically studied …
encoded by Dip2a gene. Dip2a expression pattern has never been systematically studied …
δEF1 associates with DNMT1 and maintains DNA methylation of the E‐cadherin promoter in breast cancer cells
A Fukagawa, H Ishii, K Miyazawa, M Saitoh - Cancer medicine, 2015 - Wiley Online Library
Abnormal DNA methylation at the C‐5 position of cytosine (5mC) of CpG dinucleotides is a
well‐known epigenetic feature of cancer. Levels of E‐cadherin, which is regularly expressed …
well‐known epigenetic feature of cancer. Levels of E‐cadherin, which is regularly expressed …