[HTML][HTML] Loss of DIP2C in RKO cells stimulates changes in DNA methylation and epithelial-mesenchymal transition

C Larsson, MA Ali, T Pandzic, AM Lindroth, L He… - BMC cancer, 2017 - Springer
Background The disco-interacting protein 2 homolog C (DIP2C) gene is an uncharacterized
gene found mutated in a subset of breast and lung cancers. To understand the role of DIP2C …

Heterozygous loss of Dip2B enhances tumor growth and metastasis by altering immune microenvironment

S Adlat, F Hayel, Y Chen, RK Sah, ZM Oo… - International …, 2022 - Elsevier
Cancer is caused by abnormal cell growth and metastasis to other tissues. Development of
cancers is complex and underlining mechanisms are mostly unknown. Disco-interacting …

DIP2C expression in breast cancer and its clinical significance

J Li, JL Ping, B Ma, YR Chen, LQ Li - Pathology-Research and Practice, 2017 - Elsevier
Introduction The aim of this study was to investigate DIP2C expression in different subtypes
of breast cancer tissues and cell lines and its correlation with clinicopathologic and …

[HTML][HTML] Lysine demethylase 2A expression in cancer-associated fibroblasts promotes breast tumour growth

JY Chen, CF Li, YS Lai, WC Hung - British Journal of Cancer, 2021 - nature.com
Background Our previous study demonstrated that lysine demethylase 2A (KDM2A)
enhances stemness in breast cancer cells. This demethylase is also highly expressed in …

Histone demethylase KDM7A is required for stem cell maintenance and apoptosis inhibition in breast cancer

Z Meng, Y Liu, J Wang, H Fan, H Fang… - Journal of Cellular …, 2020 - Wiley Online Library
Histone demethylase KDM7A regulates neuronal differentiation and development in
mammals. In this study, we found that KDM7A was also required for breast cancer stem cells …

Lysine demethylase KDM3A regulates breast cancer cell invasion and apoptosis by targeting histone and the non-histone protein p53

S Ramadoss, G Guo, CY Wang - Oncogene, 2017 - nature.com
Invasive growth and apoptosis resistance of breast cancer cells are associated with
metastasis and disease relapse. Here we identified that the lysine-specific demethylase …

[HTML][HTML] Genome-wide DNA methylation analysis of breast cancer MCF-7/Taxol cells with MeDIP-Seq

Y Shi, W Gong, X Gong, P Wang, X Zhao - PloS one, 2020 - journals.plos.org
Breast cancer (BC) is the most frequently diagnosed tumor in women worldwide. Although
the combination of surgery and Taxol chemotherapy can achieve a certain therapeutic effect …

Loss of desmocollin 1-3 and homeobox genes PITX1 and CDX2 are associated with tumor progression and survival in colorectal carcinoma

T Knösel, Y Chen, S Hotovy, U Settmacher… - International journal of …, 2012 - Springer
Background Genomewide expression profiling has identified a number of genes
differentially expressed in colorectal carcinomas (CRCs) compared to normal tissue. Some …

[HTML][HTML] Expression patterns and potential biological roles of Dip2a

L Zhang, HA Mabwi, NJ Palange, R Jia, J Ma, FB Bah… - PLoS …, 2015 - journals.plos.org
Disconnected (disco)-interacting protein 2 homolog A is a member of the DIP2 protein family
encoded by Dip2a gene. Dip2a expression pattern has never been systematically studied …

δEF1 associates with DNMT1 and maintains DNA methylation of the E‐cadherin promoter in breast cancer cells

A Fukagawa, H Ishii, K Miyazawa, M Saitoh - Cancer medicine, 2015 - Wiley Online Library
Abnormal DNA methylation at the C‐5 position of cytosine (5mC) of CpG dinucleotides is a
well‐known epigenetic feature of cancer. Levels of E‐cadherin, which is regularly expressed …