Dynamics of DNA methylation during development

M Brandeis, M Ariel, H Cedar - Bioessays, 1993 - Wiley Online Library
DNA methylation plays a role in the repression of gene expression in animal cells. In the
mouse preimplantation embryo, most genes are unmethylated but a wave of de novo …

Epigenomics in marine fishes

DCH Metzger, PM Schulte - Marine Genomics, 2016 - Elsevier
Epigenetic mechanisms are an underappreciated and often ignored component of an
organism's response to environmental change and may underlie many types of phenotypic …

DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos

DM Messerschmidt, BB Knowles… - Genes & …, 2014 - genesdev.cshlp.org
Methylation of DNA is an essential epigenetic control mechanism in mammals. During
embryonic development, cells are directed toward their future lineages, and DNA …

DNA methylation variation trends during the embryonic development of chicken

S Li, Y Zhu, L Zhi, X Han, J Shen, Y Liu, J Yao… - PLoS One, 2016 - journals.plos.org
The embryogenesis period is critical for epigenetic reprogramming and is thus of great
significance in the research field of poultry epigenetics for elucidation of the trends in DNA …

Dynamic regulation of DNA methylation during mammalian development

S Guibert, T Forné, M Weber - Epigenomics, 2009 - Taylor & Francis
DNA methylation occurs on cytosines, is catalyzed by DNA methyltransferases (DNMTs),
and is present at high levels in all vertebrates. DNA methylation plays essential roles in …

Computational approaches for understanding the evolution of DNA methylation in animals

SV Yi, MAD Goodisman - Epigenetics, 2009 - Taylor & Francis
DNA methylation is implicated in modulating gene transcription in a wide array of taxa.
However, a complete understanding of the specific function of DNA methylation requires …

Role of epigenetics in zebrafish development

S Balasubramanian, A Raghunath, E Perumal - Gene, 2019 - Elsevier
The role of epigenetics in development has garnered attention in recent years due to their
ability to modulate the embryonic developmental gene expression in response to the …

DNA methylation in early development

A Razin, R Shemer - Human Molecular Genetics, 1995 - academic.oup.com
Several lines of evidence strongly suggest that DNA methylation is involved in embryo
development. Perhaps the most direct evidence comes from experiments with …

A unique regulatory phase of DNA methylation in the early mammalian embryo

ZD Smith, MM Chan, TS Mikkelsen, H Gu, A Gnirke… - Nature, 2012 - nature.com
DNA methylation is highly dynamic during mammalian embryogenesis. It is broadly
accepted that the paternal genome is actively depleted of 5-methylcytosine at fertilization …

DNA methylation from embryo to adult

A Razin, T Kafri - Progress in nucleic acid research and molecular …, 1994 - Elsevier
Publisher Summary This chapter discusses the deoxyribonucleic acid (DNA) methylation
from embryo to adult. The existence of tissue-specific methylation patterns and the results of …