Global changes in genomic methylation levels during early development of the zebrafish embryo
AA Mhanni, RA McGowan - Development genes and evolution, 2004 - Springer
We have examined the methylation status of the zebrafish genome during early
embryogenesis and we find evidence that methylation fluxes do occur in that organism. The …
embryogenesis and we find evidence that methylation fluxes do occur in that organism. The …
A role for DNA methylation in gastrulation and somite patterning
CC Martin, L Laforest, MA Akimenko, M Ekker - Developmental biology, 1999 - Elsevier
DNA methylation constitutes an important epigenetic factor in the control of genetic
information. In this study, we analyzed expression of the DNA methyltransferase gene and …
information. In this study, we analyzed expression of the DNA methyltransferase gene and …
[HTML][HTML] Sperm, but not oocyte, DNA methylome is inherited by zebrafish early embryos
methylcytosine is a major epigenetic modification that is sometimes called" the fifth
nucleotide." However, our knowledge of how offspring inherit the DNA methylome from …
nucleotide." However, our knowledge of how offspring inherit the DNA methylome from …
DNA methylation at promoter regions regulates the timing of gene activation in Xenopus laevis embryos
I Stancheva, O El-Maarri, J Walter, A Niveleau… - Developmental …, 2002 - Elsevier
The levels of genomic DNA methylation in vertebrate species display a wide range of
developmental dynamics. Here, we show that in contrast to mice, the paternal genome of the …
developmental dynamics. Here, we show that in contrast to mice, the paternal genome of the …
Temporal and regional changes in DNA methylation in the embryonic, extraembryonic and germ cell lineages during mouse embryo development
M Monk, M Boubelik, S Lehnert - Development, 1987 - journals.biologists.com
This paper shows stage-and tissue-specific global demethylation and remethylation
occurring during embryonic development. The egg genome is strikingly undermethylated …
occurring during embryonic development. The egg genome is strikingly undermethylated …
Absence of genome-wide changes in DNA methylation during development of the zebrafish
D Macleod, VH Clark, A Bird - Nature genetics, 1999 - nature.com
Fig. 1 High levels of DNA methylation in gametes and early embryonic stages of zebrafish. a,
A Southern blot of DNA samples (100 ng) from sperm, adult tail and embryonic stages (2.2 h …
A Southern blot of DNA samples (100 ng) from sperm, adult tail and embryonic stages (2.2 h …
Variant Histone H2afv reprograms DNA methylation during early zebrafish development
B Madakashira, L Corbett, C Zhang, P Paoli… - Epigenetics, 2017 - Taylor & Francis
The DNA methylome is re-patterned during discrete phases of vertebrate development. In
zebrafish, there are 2 waves of global DNA demethylation and re-methylation: the first …
zebrafish, there are 2 waves of global DNA demethylation and re-methylation: the first …
[HTML][HTML] Developmental features of DNA methylation during activation of the embryonic zebrafish genome
Background Zygotic genome activation (ZGA) occurs at the mid-blastula transition (MBT) in
zebrafish and is a period of extensive chromatin remodeling. Genome-scale gametic …
zebrafish and is a period of extensive chromatin remodeling. Genome-scale gametic …
DNA methylation profiling in zebrafish
DNA methylation on cytosine in vertebrates such as zebrafish serves to silence gene
expression by interfering with the binding of certain transcription factors and through the …
expression by interfering with the binding of certain transcription factors and through the …
Immunological detection of changes in genomic DNA methylation during early zebrafish development
AB MacKay, AA Mhanni, RA McGowan, PH Krone - Genome, 2007 - cdnsciencepub.com
DNA methylation reprogramming, the erasure of DNA methylation patterns shortly after
fertilization and their reestablishment during subsequent early development, is essential for …
fertilization and their reestablishment during subsequent early development, is essential for …
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