Epigenetics and the Developmental Origins of Health and Disease: Parental environment signalling to the epigenome, critical time windows and sculpting the adult …

S Safi-Stibler, A Gabory - Seminars in cell & developmental biology, 2020 - Elsevier
Abstract The literature about Developmental Origins of Health and Disease (DOHaD)
studies is considerably growing. Maternal and paternal environment, during all the …

A conceptual framework for the developmental origins of health and disease

PD Gluckman, MA Hanson, T Buklijas - Journal of developmental …, 2010 - cambridge.org
In the last decades, the developmental origins of health and disease (DOHaD) have
emerged as a vigorous field combining experimental, clinical, epidemiological and public …

The developmental origins of health and disease (DOHaD) concept: past, present, and future

PD Gluckman, T Buklijas, MA Hanson - The epigenome and developmental …, 2016 - Elsevier
The “developmental origins of health and disease”(DOHaD) is a concept that has emerged
over the past 50 years, linking the state of health and risk from disease in later childhood …

Epigenetic epidemiology of the developmental origins hypothesis

RA Waterland, KB Michels - Annu. Rev. Nutr., 2007 - annualreviews.org
Extensive human epidemiologic and animal model data indicate that during critical periods
of prenatal and postnatal mammalian development, nutrition and other environmental stimuli …

Developmental plasticity, epigenetics and human health

FM Low, PD Gluckman, MA Hanson - Evolutionary Biology, 2012 - Springer
The unrelenting rise in global rates of non-communicable disease has necessitated a
thorough re-evaluation of the current use of adult-and lifestyle-based strategies to curb the …

Epigenetic studies in developmental origins of health and disease: pitfalls and key considerations for study design and interpretation

L Yamada, S Chong - Journal of developmental origins of health and …, 2017 - cambridge.org
The field of Developmental Origins of Health and Disease (DOHaD) seeks to understand the
relationships between early-life environmental exposures and long-term health and disease …

Early life events and their consequences for later disease: a life history and evolutionary perspective

PD Gluckman, MA Hanson… - American journal of …, 2007 - Wiley Online Library
Biomedical science has little considered the relevance of life history theory and evolutionary
and ecological developmental biology to clinical medicine. However, the observations that …

Developmental origins of health and disease: brief history of the approach and current focus on epigenetic mechanisms

PD Wadhwa, C Buss, S Entringer… - Seminars in …, 2009 - thieme-connect.com
ABSTRACT “Barker's hypothesis” emerged almost 25 years ago from epidemiological
studies of birth and death records that revealed a high geographic correlation between rates …

Epigenetic responses and the developmental origins of health and disease

D Goyal, SW Limesand, R Goyal - Journal of Endocrinology, 2019 - joe.bioscientifica.com
Maternal and paternal factors influence offspring development and program its genome for
successful postnatal life. Based on the stressors during gestation, the pregnant female …

Environmental monitoring and the developmental origins of health and disease

DL Almeida, A Pavanello, LP Saavedra… - … origins of health and …, 2019 - cambridge.org
Early-life chronic exposure to environmental contaminants, such as bisphenol-A, particulate
matter air pollution, organophosphorus pesticides, and pharmaceutical drugs, among …