Melatonin: an introduction to its physiological and pharmacological effects in humans

B Claustrat - Melatonin and Melatonergic Drugs in Clinical Practice, 2014 - Springer
Melatonin is a methoxyindole that, under normal environmental conditions, is synthesized
and secreted principally by the pineal gland at night. The endogenous rhythm of secretion is …

The basic physiology and pathophysiology of melatonin

B Claustrat, J Brun, G Chazot - Sleep medicine reviews, 2005 - Elsevier
Melatonin is a methoxyindole synthesized and secreted principally by the pineal gland at
night under normal environmental conditions. The endogenous rhythm of secretion is …

Clinical uses of melatonin: evaluation of human trials

EJ Sánchez-Barceló, MD Mediavilla… - Current medicinal …, 2010 - ingentaconnect.com
During the last 20 years, numerous clinical trials have examined the therapeutic usefulness
of melatonin in different fields of medicine. The objective of this article is to review, in depth …

Melatonin: pharmacology, functions and therapeutic benefits

S Tordjman, S Chokron, R Delorme… - Current …, 2017 - ingentaconnect.com
Background: Melatonin synchronizes central but also peripheral oscillators (fetal adrenal
gland, pancreas, liver, kidney, heart, lung, fat, gut, etc.), allowing temporal organization of …

Melatonin: from hormone to drug?

B Claustrat, M Geoffriau, J Brun, G Chazot - Pathologie-biologie, 1996 - europepmc.org
Melatonin is an indole hormone that is produced by the pineal gland, mainly at night, with a
peak around 3.00 am under normal environmental conditions. This endogenic secretion …

Melatonin in humans: a biochemical marker of the circadian clock and an endogenous synchronizer

B Claustrat, M Geoffriau, J Brun, G Chazot - Neurophysiologie Clinique …, 1995 - Elsevier
Melatonin (MLT) is a methoxyindole secreted principally by the pineal gland. It is
synthesized at night under normal environmental conditions. The endogenous rhythm of …

Melatonin and biological rhythms

P Pevet - Therapie, 1998 - europepmc.org
Melatonin is synthesized and secreted by the pineal gland during the dark period of the light-
dark cycle. This rhythmic nocturnal melatonin secretion is generated directly by the circadian …

Melatonin and human rhythms

J Arendt - Chronobiology international, 2006 - Taylor & Francis
Melatonin signals time of day and time of year in mammals by virtue of its pattern of
secretion, which defines 'biological night.'It is supremely important for research on the …

Melatonin, Receptors, Mechanism, and Uses.

SH Omar, N Saba - Systematic Reviews in Pharmacy, 2010 - search.ebscohost.com
Melatonin, a hormone produced primarily by the pineal gland, is also secreted from the gut
and eye during darkness. There are three classes of melatonin receptors, MT< sub> 1, MT< …

Basic aspects of melatonin action

DP Cardinali, P Pévet - Sleep medicine reviews, 1998 - Elsevier
Melatonin is synthesized and secreted during the dark period of the light-dark cycle. Thus,
melatonin has an obvious association with sleep, at least in diurnal animals. Rhythmic …