DNA methylation contributes to the control of gene expression and plays an essential role in
cellular physiology. Well-defined patterns of DNA methylation are established and fixed …

The promise of epigenome-wide association studies and cancer-specific somatic DNA
methylation changes in improving our understanding of cancer, coupled with the decreasing …

Background Many different methods exist to adjust for variability in cell-type mixture
proportions when analyzing DNA methylation studies. Here we present the result of an …

DNA methylation is an epigenetic mechanism that is related to mammalian cellular
differentiation, gene expression regulation, and disease. In several studies, DNA …

DNA methylation is a stable epigenetic mechanism that has important roles in the normal
function of a cell and therefore also in disease etiology. Accurate measurements of normal …

DNA methylation is an important mechanism regulating gene transcription, and its role in
carcinogenesis has been extensively studied. Hyper and hypomethylation of genes is a …

DNA methylation is an essential epigenetic modification that plays a key role associated with
the regulation of gene expression during differentiation, but in disease states such as …

The genomes of many animals, plants and fungi are tagged by methylation of DNA cytosine.
To understand the biological significance of this epigenetic mark it is essential to know …

DNA methylation is one of the most commonly studied epigenetic marks, due to its role in
disease and development. Illumina methylation arrays have been extensively used to …

BACKGROUND: In the recent past large progress has been made in the analysis of the
epigenome, the entirety of epigenetic modifications, and its meaning for the implementation …