The DNA methylation landscape in cancer
As one of the most abundant and well-studied epigenetic modifications, DNA methylation
plays an essential role in normal development and cellular biology. Global alterations to the …
plays an essential role in normal development and cellular biology. Global alterations to the …
Dynamic DNA methylation across diverse human cell lines and tissues
As studies of DNA methylation increase in scope, it has become evident that methylation has
a complex relationship with gene expression, plays an important role in defining cell types …
a complex relationship with gene expression, plays an important role in defining cell types …
Validation of a DNA methylation microarray for 850,000 CpG sites of the human genome enriched in enhancer sequences
S Moran, C Arribas, M Esteller - Epigenomics, 2016 - Taylor & Francis
Aim: DNA methylation is the best known epigenetic mark. Cancer and other pathologies
show an altered DNA methylome. However, delivering complete DNA methylation maps is …
show an altered DNA methylome. However, delivering complete DNA methylation maps is …
Genome-Wide Dna Methylation Profiling Using Infinium® Assay
M Bibikova, J Le, B Barnes, S Saedinia-Melnyk… - …, 2009 - Taylor & Francis
Aims: Bisulfite sequence analysis of individual CpG sites within genomic DNA is a powerful
approach for methylation analysis in the genome. The major limitation of bisulfite-based …
approach for methylation analysis in the genome. The major limitation of bisulfite-based …
Whole-genome DNA methylation profiling using MethylCap-seq
AB Brinkman, F Simmer, K Ma, A Kaan, J Zhu… - Methods, 2010 - Elsevier
MethylCap-seq is a robust procedure for genome-wide profiling of DNA methylation. The
approach consists of the capture of methylated DNA using the MBD domain of MeCP2, and …
approach consists of the capture of methylated DNA using the MBD domain of MeCP2, and …
Design, measurement and processing of region-specific DNA methylation assays: the mass spectrometry-based method EpiTYPER
HED Suchiman, RC Slieker, D Kremer… - Frontiers in …, 2015 - frontiersin.org
EpiTYPER® is a mass spectrometry-based bisulfite sequencing method that enables region-
specific DNA methylation analysis in a quantitative and high-throughput fashion. The …
specific DNA methylation analysis in a quantitative and high-throughput fashion. The …
GeMes, clusters of DNA methylation under genetic control, can inform genetic and epigenetic analysis of disease
Epigenetic marks such as DNA methylation have generated great interest in the study of
human disease. However, studies of DNA methylation have not established population …
human disease. However, studies of DNA methylation have not established population …
CpGassoc: an R function for analysis of DNA methylation microarray data
With the increasing availability of high-density methylation microarrays, there has been
growing interest in analysis of DNA methylation data. We have developed CpGassoc, an R …
growing interest in analysis of DNA methylation data. We have developed CpGassoc, an R …
Quantitative cross-validation and content analysis of the 450k DNA methylation array from Illumina, Inc.
J Roessler, O Ammerpohl, J Gutwein, B Hasemeier… - BMC research …, 2012 - Springer
Background The newly released 450k DNA methylation array from Illumina, Inc. offers the
possibility to analyze more than 480,000 individual CpG sites in a user friendly standardized …
possibility to analyze more than 480,000 individual CpG sites in a user friendly standardized …
A Comparison of the Whole Genome Approach of MeDIP-Seq to the Targeted Approach of the Infinium HumanMethylation450 BeadChip® for Methylome Profiling
C Clark, P Palta, CJ Joyce, C Scott, E Grundberg… - PloS one, 2012 - journals.plos.org
DNA methylation is one of the most studied epigenetic marks in the human genome, with the
result that the desire to map the human methylome has driven the development of several …
result that the desire to map the human methylome has driven the development of several …